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            • Primary Antibodies ›
            • SLC28A1 Antibodies

            Alomone Labs, LTD

            SLC28A1 (CNT1) Polyclonal Antibody

            View all (5) SLC28A1 antibodies
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            Cite SLC28A1 (CNT1) Polyclonal Antibody

            • Antibody Testing Data (1)
            Application
            SLC28A1 (CNT1) Antibody in Western Blot (WB)
            Group 53 Created with Sketch.

            FIGURE: 1 / 1

            SLC28A1 (CNT1) Antibody (ANT-061-200UL) in WB

            Western blot analysis of rat kidney (lanes 1 and 4), rat liver (lanes 2 and 5) and mouse kidney (lanes 3 and 6) lysates: - 1-3. Anti-SLC28A1 (CNT1) Antibody (#ANT-061), (1:200).4-6. Anti-SLC28A1 (CNT1) Antibody , preincubated with SLC28A1/CNT1 Blocking Peptide (#BLP-NT061).
            View Product

            SLC28A1 (CNT1) Antibody in Western Blot (WB)

            Product Details

            ANT-061-200UL

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:200
            -
            Product Specifications

            Species Reactivity

            Mouse, Rat

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            (C)ENMGAEFLESMEEGR, corresponding to amino acid residues 22-36 of rat SLC28A1, Intracellular, N-terminus
            View immunogen

            Conjugate

            Unconjugated

            Form

            Lyophilized

            Concentration

            0.8 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            PBS, pH 7.4, with 1% BSA

            Contains

            0.05% sodium azide

            Storage conditions

            -20°C, Avoid Freeze/Thaw Cycles

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            Product Specific Information

            Reconstitution: 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

            Target Information

            Nucleosides play a role in signaling in several physiologic systems, and synthetic analogs of natural nucleosides are often used to treat neoplastic and viral diseases. Plasma membrane transport of nucleosides is mediated by equilibrative and concentrative nucleoside transporters, which may have specificity for purines or pyrimidines. The deduced human 650 amino acid concentrative nucleoside transporter 1 (CNT1) protein is 83% identical to the rat protein and is expressed in the intestine, kidney and liver. CNT1, also designated solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 (SLC28A1), expedites sodium-dependent fluxes of uridine, azidodeoxythymidine (AZT) and adenosine, but not of guanosine or deoxyadenosine, which undergo net renal secretion. CNT1 activity may serve as a putative mechanism for renal reabsorption of physiologic nucleosides and synthetic nucleoside drugs.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: CNT 1; Concentrative nucleoside transporter 1; Na(+)/nucleoside cotransporter 1; Sodium-coupled nucleoside transporter 1; Sodium/nucleoside cotransporter 1; solute carrier family 28 (sodium-coupled nucleoside transporter), member 1; Solute carrier family 28 member 1; solute carrier family 28, member 1

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            Gene Aliases: Cnt1; Slc28a1

            View more View less

            UniProt ID: (Rat) Q62674, (Mouse) E9PXX9

            View more View less

            Entrez Gene ID: (Rat) 116642, (Mouse) 434203

            View more View less

            Function(s)

            nucleoside binding pyrimidine nucleobase transmembrane transporter activity nucleoside:sodium symporter activity pyrimidine- and adenine-specific:sodium symporter activity transporter

            Process(es)

            purine nucleobase transport pyrimidine nucleobase transport pyrimidine-containing compound transmembrane transport nucleoside transmembrane transport sodium ion transmembrane transport
            It has to be done as per old AB suggested Products section.
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            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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