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SLC2A9 Polyclonal Antibody

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Antibody Testing Data (3)

SLC2A9 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 3

SLC2A9 Antibody (26486-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human liver tissue slide using 26486-1-AP (SLC2A9 antibody) at dilution of 1:200 (under 40x lens).

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Product Details

26486-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 19 publications 19 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SLC2A9 Fusion Protein Ag24135 (443-511 aa encoded by BC018897)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.47 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: IQKSLDTYC FLVFATICIT GAIYLYFVLP ETKNRTYAEI SQAFSKRNKA YPPEEKIDSA VTDGKINGRP (443-511 aa encoded by BC018897)

Target Information

GLUT9, or SLC2A9, is a member of the SLC2A facilitative glucose transporter family. Members of this family play a significant role in maintaining glucose homeostasis. GLUT9 may play a role in the development and survival of chondrocytes in cartilage matrices. Two transcript variants encoding distinct isoforms have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Hypouricemic and nephroprotective effects of palmatine from Cortex Phellodendri Amurensis: A uric acid modulator targeting Keap1-Nrf2/NLRP3 axis.

Journal of ethnopharmacology

Ai G,Huang R,Xie J,Zhong L,Wu X,Qin Z,Su Z,Chen J,Yang X,Dou Y

Mon Jan 30 00:00:00 EST 2023

Simiao San alleviates hyperuricemia and kidney inflammation by inhibiting NLRP3 inflammasome and JAK2/STAT3 signaling in hyperuricemia mice.

Journal of ethnopharmacology

Zhang Y,Wang S,Dai X,Liu T,Liu Y,Shi H,Yin J,Xu T,Zhang Y,Zhao D,Sukhorukov V,Orekhov AN,Gao S,Wang L,Zhang D

Thu Aug 10 00:00:00 EDT 2023

Amelioration effects of α-viniferin on hyperuricemia and hyperuricemia-induced kidney injury in mice.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Guo XL,Gao YY,Yang YX,Zhu QF,Guan HY,He X,Zhang CL,Wang Y,Xu GB,Zou SH,Wei MC,Zhang J,Zhang JJ,Liao SG

Tue Jul 25 00:00:00 EDT 2023

Ferulic acid supplementation alleviates hyperuricemia in high-fructose/fat diet-fed rats via promoting uric acid excretion and mediating the gut microbiota.

Food & function

Zhang N,Zhou J,Zhao L,Zhao Z,Wang S,Zhang L,Zhou F

Mon Feb 06 00:00:00 EST 2023

Naringenin Ameliorates Hyperuricemia by Regulating Renal Uric Acid Excretion via the PI3K/AKT Signaling Pathway and Renal Inflammation through the NF-κB Signaling Pathway.

Journal of agricultural and food chemistry

Yang B,Xin M,Liang S,Huang Y,Li J,Wang C,Liu C,Song X,Sun J,Sun W

Wed Jan 25 00:00:00 EST 2023

Oxyberberrubine, a novel liver microsomes-mediated secondary metabolite of berberine, alleviates hyperuricemic nephropathy in mice.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Zhong L,Lin Y,Gong S,Wu X,Liu Y,Chen J,Li Y,Yan F,Su Z,Xie Q

Sun Jan 01 00:00:00 EST 2023

Apigenin Ameliorates Hyperuricemia and Renal Injury through Regulation of Uric Acid Metabolism and JAK2/STAT3 Signaling Pathway.

Pharmaceuticals (Basel, Switzerland)

Liu T,Gao H,Zhang Y,Wang S,Lu M,Dai X,Liu Y,Shi H,Xu T,Yin J,Gao S,Wang L,Zhang D

Mon Nov 21 00:00:00 EST 2022

Autophagy-dependent Na⁺-K⁺-ATPase signalling and abnormal urate reabsorption in hyperuricaemia-induced renal tubular injury.

European journal of pharmacology

Guan H,Lin H,Wang X,Xu Y,Zheng Y,Zhou X,Diao X,Ye Z,Xiao J

Sat Oct 15 00:00:00 EDT 2022

Berberine Attenuates Hyperuricemia by Regulating Urate Transporters and Gut Microbiota.

The American journal of Chinese medicine

Shan B,Wu M,Chen T,Tang W,Li P,Chen J

Fri Nov 25 00:00:00 EST 2022

Therapeutic effects and mechanisms of N-(9,10-anthraquinone-2-ylcarbonyl) xanthine oxidase inhibitors on hyperuricemia.

Frontiers in pharmacology

Gao T,Xu J,Xiao Y,Li J,Hu W,Su X,Shen X,Yu W,Chen Z,Huang B,Li H,Wang X

Tue Sep 20 00:00:00 EDT 2022

Effects of black tea and black brick tea with fungal growth on lowering uric acid levels in hyperuricemic mice.

Journal of food biochemistry

Yuan D,Lin L,Peng Y,Zhou Y,Li L,Xiao W,Gong Z

Fri Jul 01 00:00:00 EDT 2022

Resveratrol affects the expression of uric acid transporter by improving inflammation.

Molecular medicine reports

Zhang X,Nie Q,Zhang Z,Zhao J,Zhang F,Wang C,Wang X,Song G

Sun Aug 01 00:00:00 EDT 2021

Sonneratia apetala seed oil attenuates potassium oxonate/hypoxanthine-induced hyperuricemia and renal injury in mice.

Food & function

Chen J,Xu L,Jiang L,Wu Y,Wei L,Wu X,Xiao S,Liu Y,Gao C,Cai J,Su Z

Mon Oct 04 00:00:00 EDT 2021

Berberrubine attenuates potassium oxonate- and hypoxanthine-induced hyperuricemia by regulating urate transporters and JAK2/STAT3 signaling pathway.

European journal of pharmacology

Lin G,Yu Q,Xu L,Huang Z,Mai L,Jiang L,Su Z,Xie J,Li Y,Liu Y,Lin Z,Chen J

Sun Dec 05 00:00:00 EST 2021

Anti-Hyperuricemic and Nephroprotective Effects of Dihydroberberine in Potassium Oxonate- and Hypoxanthine-Induced Hyperuricemic Mice.

Frontiers in pharmacology

Xu L,Lin G,Yu Q,Li Q,Mai L,Cheng J,Xie J,Liu Y,Su Z,Li Y

Sat May 08 00:00:00 EDT 2021

Withaferin A protects against hyperuricemia induced kidney injury and its possible mechanisms.

Bioengineered

Zhao X,Wang J,Tang L,Li P,Ru J,Bai Y

Wed Dec 01 00:00:00 EST 2021

Anti-hyperuricemic potential of stevia (Stevia rebaudiana Bertoni) residue extract in hyperuricemic mice.

Food & function

Mehmood A,Zhao L,Ishaq M,Xin W,Zhao L,Wang C,Hossen I,Zhang H,Lian Y,Xu M

Wed Jul 22 00:00:00 EDT 2020

Conjugated Linoleic Acid Ameliorates High Fructose-Induced Hyperuricemia and Renal Inflammation in Rats via NLRP3 Inflammasome and TLR4 Signaling Pathway.

Molecular nutrition & food research

Tan J,Wan L,Chen X,Li X,Hao X,Li X,Li J,Ding H

Sat Jun 01 00:00:00 EDT 2019

MiR-143-3p directly targets GLUT9 to reduce uric acid reabsorption and inflammatory response of renal tubular epithelial cells.

Biochemical and biophysical research communications

Zhou Z,Dong Y,Zhou H,Liu J,Zhao W

Tue Sep 24 00:00:00 EDT 2019

Impaired Na⁺-K⁺-ATPase signaling in renal proximal tubule contributes to hyperuricemia-induced renal tubular injury.

Experimental & molecular medicine

Xiao J,Zhang X,Fu C,Yang Q,Xie Y,Zhang Z,Ye Z

Fri Mar 02 00:00:00 EST 2018

Impaired Na⁺-K⁺-ATPase signaling in renal proximal tubule contributes to hyperuricemia-induced renal tubular injury.

Experimental & molecular medicine

Xiao J,Zhang X,Fu C,Yang Q,Xie Y,Zhang Z,Ye Z

Fri Mar 02 00:00:00 EST 2018

Bioinformatics

Protein Aliases: facilitated glucose transporter, type 9; Glucose transporter type 9; GLUT-9; human glucose transporter-like protein-9; solute carrier family 2 (facilitated glucose transporter), member 9; Solute carrier family 2, facilitated glucose transporter member 9; Urate transporter; urate voltage-driven efflux transporter 1

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Gene Aliases: GLUT9; GLUTX; SLC2A9; SLC2a9A; SLC2A9B; UAQTL2; URATv1

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UniProt ID: (Human) Q9NRM0, (Mouse) Q3T9X0

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Entrez Gene ID: (Human) 56606, (Mouse) 117591

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Function(s)

sugar:proton symporter activity glucose transmembrane transporter activity urate transmembrane transporter activity transmembrane transporter activity

Process(es)

glucose transport proton transport carbohydrate transmembrane transport hexose transmembrane transport glucose import urate metabolic process cation transmembrane transport organic acid transmembrane transport glucose transmembrane transport

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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SLC2A9 Polyclonal Antibody

SLC2A9 Antibody (26486-1-AP) in IHC (P)

Product Details

26486-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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