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Product Details
PA5-65535
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human SLC30A1. Recombinant protein control fragment (Product #RP-106209).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2665294
Product Specific Information
Immunogen sequence: RNVEGVEEVHE LHVWQLAGSR IIATAHIKCE DPTSYMEVAK TIKDVFHNHG IHATTIQPEF ASVGSKSSVV PCELACRTQC ALKQCCGTLP QAPSGKDAEK TPAVSISCLE LSNNLEKKPR RTKAENIPAV VIEIKNMPNK QPESS
Highest antigen sequence identity to the following orthologs - mouse 89%, rat 90%.
Target Information
Zinc, an essential element required for cell proliferation and differentiation, plays a role in a diverse array of cellular functions, including acting as a cofactor for numerous enzymes and transcription factors and as a neuroregulator. The zinc transporter (ZnT) family regulates the supply of zinc within cells, and its members are characterized by containing six membrane-spanning domains, a large histidine-rich intracellular loop, and a C-terminal tail. ZnT-1, a ubiquitous protein of approximately 60 kDa, localizes to the plasma membrane to aid in the export of zinc out of cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Proton-coupled zinc antiporter SLC30A1; solute carrier family 30 (zinc transporter), member 1; Solute carrier family 30 member 1; Zinc transporter 1; znT-1
Gene Aliases: SLC30A1; ZNT1; ZRC1
UniProt ID: (Human) Q9Y6M5
Entrez Gene ID: (Human) 7779
in utero embryonic development
zinc II ion transport
cellular calcium ion homeostasis
cellular zinc ion homeostasis
response to zinc ion
negative regulation of neurotransmitter secretion
regulation of sequestering of zinc ion
calcium ion import
cadmium ion transmembrane transport
zinc II ion transmembrane transport
negative regulation of zinc ion transmembrane import
detoxification of cadmium ion
negative regulation of calcium ion import
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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