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Antiporter transporting nucleotide sugars such as UDP-N-acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP-mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Nucleotide sugar transporter SLC35D2; Solute carrier family 35 member D2; UDP-galactose transporter-related protein 8; UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter; UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter; UGTrel8
Gene Aliases: 5730408I21Rik; hfrc; mUGTrel8; Slc35d2; SQV7L; UGTrel8
UniProt ID: (Mouse) Q762D5
Entrez Gene ID: (Mouse) 70484
Molecular Function:
secondary carrier transporter
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