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Recommended positive controls: human erythrocytes.
This antibody does not cross react with porcine, mouse, bovine, canine, guinea pig, or equine Band 3.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The Band 3 protein is the most abundant integral protein of human erythrocyte membranes and functions as the major anion transporter polypeptide of erythrocytes. Band 3 is a 90-100 kDa protein, its microheterogeneity is ascribed mainly to the structural heterogeneity of the carbohydrate moiety. The C-terminal portion of the molecule spans the membrane several times, and is responsible for anion transport. The N-terminal portion, comprising almost half of the polypeptide chain of Band 3, is located inside the red cell and interacts with cytoskeletal and cytoplasmic proteins such as ankyrin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AE 1; Anion exchange protein 1; anion exchanger 1; anion exchanger-1; Band 3 anion transport protein; CAMP; CD233; Diego blood group; erythrocyte membrane protein band 3; erythroid anion exchange protein; Froese blood group; MGC116750; MGC116753; MGC126619; MGC126623; solute carrier family 4 (anion exchanger), member 1 (Diego blood group); Solute carrier family 4 member 1; solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group); solute carrier family 4, anion exchanger, number 1; Swann blood group; Waldner blood group; Wright blood group; ZNF828
Gene Aliases: AE1; BND3; CD233; CHC; DI; EMPB3; EPB3; FR; RTA1A; SAO; SLC4A1; SPH4; SW; WD; WD1; WR
UniProt ID: (Human) P02730
Entrez Gene ID: (Human) 6521
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