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Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Gibbon, Baboon, Monkey (94%); Marmoset (81%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Has electrogenic activity in response to glucose, and may function as a glucose sensor (PubMed:13130073, PubMed:17110502, PubMed:20421923, PubMed:22766068). Mediates influx of sodium ions into the cell but does not transport sugars (PubMed:13130073, PubMed:22766068). Also potently activated by imino sugars such as deoxynojirimycin (DNJ) (PubMed:17110502, PubMed:20421923, PubMed:22766068). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: low affinity sodium glucose cotransporter; Na(+)/glucose cotransporter 3; Probable glucose sensor protein SLC5A4; sodium transporter; sodium/glucose cotransporter 3; solute carrier family 5 (glucose activated ion channel), member 4; solute carrier family 5 (low affinity glucose cotransporter), member 4; solute carrier family 5 (neutral amino acid transporters, system A), member 4; Solute carrier family 5 member 4
Gene Aliases: DJ90G24.4; SAAT1; SGLT3; SLC5A4
UniProt ID: (Human) Q9NY91
Entrez Gene ID: (Human) 6527
Molecular Function:
secondary carrier transporter
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