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SLC9A6 Antibody (PA5-121178) in WB
Western blot analysis of SLC9A6 in extracts of various cell lines. Samples were incubated with SLC9A6 Polyclonal antibody (Product # PA5-121178) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-121178
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 542-701 of human SLC9A6 (NP_001036002.1).
Conjugate
Form
Liquid
Concentration
0.34 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2914750
Product Specific Information
Positive test controls include: Mouse lung, Mouse heart, Mouse skeletal muscle. The target is usually found in the following locations: Endosome membrane, Multi-pass membrane protein.
Immunogen sequence: VDSDQEHLGV PENERRTTKA ESAWLFRMWY NFDHNYLKPL LTHSGPPLTT TLPACCGPIA RCLTSPQAYE NQEQLKDDDS DLILNDGDIS LTYGDSTVNT EPATSSAPRR FMGNSSEDAL DRELAFGDHE LVIRGTRLVL PMDDSEPPLN LLDNTRHGPA
Target Information
Na+/H+ exchangers-1-6 (Na+/H+ antiporters, NHE-1-6) are integral membrane proteins that are expressed in most mammalian tissues where they regulate intracellular pH and cell volume. NHEs mediate the secondary active extrusion of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+). Excluding NHE-1, which is ubiquitously expressed, the NHE isoforms 2-6 have distinct tissue- and cell type-dependent expression, and inhibitiory characteristics by amiloride analogs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Na(+)/H(+) exchanger 6; NHE-6; Sodium/hydrogen exchanger; Sodium/hydrogen exchanger 6; solute carrier family 9 (sodium/hydrogen exchanger), isoform 6; solute carrier family 9 (sodium/hydrogen exchanger), member 6; Solute carrier family 9 member 6; solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
Gene Aliases: 3732426M05; 6430520C02Rik; KIAA0267; mKIAA0267; MRSA; NHE6; SLC9A6
UniProt ID: (Human) Q92581, (Mouse) A1L3P4
Entrez Gene ID: (Human) 10479, (Mouse) 236794
transport
ion transport
brain-derived neurotrophic factor receptor signaling pathway
axon extension
neuron projection morphogenesis
synapse organization
regulation of neurotrophin TRK receptor signaling pathway
regulation of intracellular pH
dendritic spine development
potassium ion transmembrane transport
dendrite extension
sodium ion import across plasma membrane
hydrogen ion transmembrane transport
proton transport
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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