Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: SLITRK5.
SLIT and NTRK-like family 5 (Slitrk5) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk5 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: leucine rich repeat containing 11; Leucine-rich repeat-containing protein 11; SLIT and NTRK-like family, member 5; SLIT and NTRK-like protein 5; slit and trk like gene 5
Gene Aliases: 2610019D03Rik; bA364G4.2; KIAA0918; LRRC11; SLITRK5
UniProt ID: (Human) O94991, (Mouse) Q810B7
Entrez Gene ID: (Human) 26050, (Mouse) 75409, (Rat) 306152
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