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Product Details
H00006604-M04
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
5B6
Immunogen
SMARCD3 (NP_001003801, 385 a.a. approximately 483 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: ISALDSKIHE TIESINQLKI QRDFMLSFSR DPKGYVQDLL RSQSRDLKVM TDVAGNPEEE RRAEFYHQPW SQEAVSRYFY CKIQQRRQEL EQSLVVRNT
Target Information
BAF60C is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 60 kDa BRG-1/Brm-associated factor subunit C; BAF60C; BRG1-associated factor 60C; chromatin remodeling complex BAF60C subunit; mammalian chromatin remodeling complex BRG1-associated factor 60C; mBAF60c; MGC111010; SWI/SNF complex 60 kDa subunit C; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3, isoform 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3; Swp73-like protein
Gene Aliases: 1500001J14Rik; 2210409C08Rik; BAF60C; CRACD3; Rsc6p; SMARCD3
UniProt ID: (Human) Q6STE5, (Mouse) Q6P9Z1
Entrez Gene ID: (Human) 6604, (Mouse) 66993, (Rat) 296732
chromatin binding
transcription coactivator activity
receptor binding
transcription factor binding
nuclear hormone receptor binding
protein binding
ligand-dependent nuclear receptor binding
ligand-dependent nuclear receptor transcription coactivator activity
chromatin/chromatin-binding, or -regulatory protein
positive regulation of neuroblast proliferation
secondary heart field specification
cardiac right ventricle formation
neural retina development
nucleosome disassembly
chromatin remodeling
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
positive regulation of G2/M transition of mitotic cell cycle
covalent chromatin modification
muscle cell differentiation
regulation of protein binding
cellular lipid metabolic process
positive regulation of transcription, DNA-templated
positive regulation of smooth muscle cell differentiation
heart morphogenesis
regulation of transcription, DNA-templated
nervous system development
chromatin modification
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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