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Invitrogen
SMCHD1 Monoclonal Antibody (CL4270)
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Application
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SMCHD1 Antibody (MA5-24709) in ICC/IF
Immunofluorecent analysis of SMCHD1 in U-2 OS cells using SMCHD1 Monoclonal Antibody (CL4270) (Product # MA5-24709). Staining shows specific staining in the nucleoplasm in green. Microtubule- and nuclear probes are visualized in red and blue, respectively (where available).
Product Details
MA5-24709
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
CL4270
Immunogen
Recombinant Human SMCHD1
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2661949
Product Specific Information
Immunogen sequence: DNGRGMTSKQL NNWAVYRLSK FTRQGDFESD HSGYVRPVPV PRSLNSDISY FGVGGKQAVF FVGQSARMIS KPADSQDVHE LVLSKED
Highest antigen sequence identity to the following orthologs - mouse 97%, rat 98%.
Target Information
Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the de novo methyltransferase DNMT3B. Required for DUX4 silencing in somatic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: SMC hinge domain-containing protein 1; Structural maintenance of chromosomes flexible hinge domain-containing protein 1
Gene Aliases: KIAA0650; SMCHD1
UniProt ID: (Human) A6NHR9
Entrez Gene ID: (Human) 23347
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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