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Immunogen sequence: GTLRRSDSQQ AVKSPPLLES PDATRESMVK LSSKLSAVSL RGIGSPSTDA SASDVHGNFA FEGIGDEDL
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 96%.
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a B41 domain. This protein interacts with the cytoplasmic domain of P-selectin, and may function in the intracellular trafficking of P-selectin. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Sorting nexin-17
Gene Aliases: KIAA0064; SNX17
UniProt ID: (Human) Q15036
Entrez Gene ID: (Human) 9784
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