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Proteintech

SORBS1 Polyclonal Antibody

4 References

View all (8) SORBS1 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (6)

Application

FIGURE: 1 / 6

SORBS1 Antibody (13854-1-AP) in WB

Mouse kidney tissue were subjected to SDS PAGE followed by western blot with 13854-1-AP (SORBS1 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

SORBS1 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

13854-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 1 publication 1 publication

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

Assay-dependent

View 2 publications 2 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse

Published species

Dog

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SORBS1 Fusion Protein Ag4828 (1-300 aa encoded by BC042612)

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

0.39 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MSSECDGGS KAVMNGLAPG SNGQDKDMDP TKICTGKGAV TLRASSSYRE TPSSSPASPQ ETRQHESKPD EWRLSSSADA NGNAQPSSLA AKGYRSVHPN LPSDKSQDAT SSSAAQPEVI VVPLYLVNTD RGQEGTARPP TPLGPLGCVP TIPATASAAS PLTFPTLDDF IPPHLQRWPH HSQPARASGS FAPISQTPPS FSPPPPLVPP APEDLRRVSE PDLTGAVSST DSSPLLNEVS SSLIGTDSQA FPSVSKPSSA YPSTTIVNPT IVLLQHNREQ QKRLSSLSDP VSERRVGEQD S (1-300 aa encoded by BC042612)

Target Information

Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Long Non-coding RNAs LOC100126784 and POM121L9P Derived From Bone Marrow Mesenchymal Stem Cells Enhance Osteogenic Differentiation via the miR-503-5p/SORBS1 Axis.

Frontiers in cell and developmental biology

Xu Y,Xin R,Sun H,Long D,Li Z,Liao H,Xue T,Zhang Z,Kang Y,Mao G

Wed Nov 10 00:00:00 UTC 2021

Long Non-coding RNAs LOC100126784 and POM121L9P Derived From Bone Marrow Mesenchymal Stem Cells Enhance Osteogenic Differentiation via the miR-503-5p/SORBS1 Axis.

Frontiers in cell and developmental biology

Xu Y,Xin R,Sun H,Long D,Li Z,Liao H,Xue T,Zhang Z,Kang Y,Mao G

Wed Nov 10 00:00:00 UTC 2021

Integrative Cell Type-Specific Multi-Omics Approaches Reveal Impaired Programs of Glial Cell Differentiation in Mouse Culture Models of DM1.

Frontiers in cellular neuroscience

González-Barriga A,Lallemant L,Dincã DM,Braz SO,Polvèche H,Magneron P,Pionneau C,Huguet-Lachon A,Claude JB,Chhuon C,Guerrera IC,Bourgeois CF,Auboeuf D,Gourdon G,Gomes-Pereira M

Wed May 26 00:00:00 UTC 2021

Sorbin and SH3 domain-containing protein 2 (SORBS2) is a component of the acto-myosin ring at the apical junctional complex in epithelial cells.

PloS one

Fredriksson-Lidman K,Van Itallie CM,Tietgens AJ,Anderson JM

Fri Nov 03 00:00:00 UTC 2017

Sorbin and SH3 domain-containing protein 2 (SORBS2) is a component of the acto-myosin ring at the apical junctional complex in epithelial cells.

PloS one

Fredriksson-Lidman K,Van Itallie CM,Tietgens AJ,Anderson JM

Fri Nov 03 00:00:00 UTC 2017

Bioinformatics

Protein Aliases: c-Cbl associated protein; c-Cbl-associated protein; CAP; DKFZp451C066; DKFZP586P1422; Fas-ligand associated factor 2; FLJ12406; OTTHUMP00000020142; OTTHUMP00000020143; OTTHUMP00000020144; OTTHUMP00000020145; Ponsin; SH3 domain protein 5; SH3P12; Sorbin and SH3 domain-containing protein 1; SORBS1

Gene Aliases: 2310065E01Rik; 9530001P15Rik; CAP; FLAF2; KIAA0894; KIAA1296; mKIAA1296; R85FL; SH3D5; SH3P12; SORB1; SORBS1

UniProt ID: (Human) Q9BX66, (Mouse) Q62417

Entrez Gene ID: (Human) 10580, (Mouse) 20411

Function(s)

actin binding SH3/SH2 adaptor activity insulin receptor binding protein binding cytoskeletal protein binding transcription factor binding protein kinase binding

Process(es)

muscle contraction cell-matrix adhesion insulin receptor signaling pathway positive regulation of signal transduction glucose transport cellular response to insulin stimulus stress fiber assembly positive regulation of glycogen biosynthetic process positive regulation of glucose import positive regulation of lipid biosynthetic process focal adhesion assembly positive regulation of establishment of protein localization to plasma membrane transport actin filament organization

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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