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Invitrogen
SPAG8 Polyclonal Antibody
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Product Details
PA5-50264
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Fusion protein corresponding to a region derived from internal residues of human sperm associated antigen 8
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2635717
Product Specific Information
The antibody detects endogenous levels of total SPAG8 protein.
Target Information
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HSD-1; SMP-1; Sperm membrane protein 1; Sperm membrane protein BS-84; Sperm-associated antigen 8; testicular tissue protein Li 177
Gene Aliases: BS-84; CILD28; CT142; HSD-1; hSMP-1; SMP1; SPAG3; SPAG8
UniProt ID: (Human) Q99932
Entrez Gene ID: (Human) 26206
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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