Proteintech

SPRR3 Polyclonal Antibody

View all (7) SPRR3 antibodies

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Antibody Testing Data (8)

SPRR3 Antibody in Immunocytochemistry (ICC/IF)

SPRR3 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 8

SPRR3 Antibody (11742-1-AP) in ICC/IF

Immunofluorescent analysis of HeLa cells using 11742-1-AP (SPRR3 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

SPRR3 Antibody in Immunocytochemistry (ICC/IF)

SPRR3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SPRR3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SPRR3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SPRR3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SPRR3 Antibody in Western Blot (WB)

SPRR3 Antibody in Western Blot (WB)

SPRR3 Antibody in Immunoprecipitation (IP)

Product Image Gallery

SPRR3 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of HeLa cells using 11742-1-AP (SPRR3 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

SPRR3 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human breast cancer using 11742-1-AP (SPRR3 antibody) at dilution of 1:100 (under 40x lens).

SPRR3 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human breast cancer using 11742-1-AP (SPRR3 antibody) at dilution of 1:100 (under 10x lens).

SPRR3 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human colon cancer using 11742-1-AP (SPRR3 antibody) at dilution of 1:100 (under 40x lens).

SPRR3 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human colon cancer using 11742-1-AP (SPRR3 antibody) at dilution of 1:100 (under 10x lens).

SPRR3 Antibody in Western Blot (WB) — Human liver tissue were subjected to SDS PAGE followed by western blot with 11742-1-AP (SPRR3 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

SPRR3 Antibody in Western Blot (WB) — HeLa cells were subjected to SDS PAGE followed by western blot with 11742-1-AP (SPRR3 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours.

SPRR3 Antibody in Immunoprecipitation (IP) — IP result of anti-SPRR3 (IP:11742-1-AP, 3ug; Detection:11742-1-AP 1:500) with COLO 320 cells lysate 1720ug.

Product Details

11742-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 8 publications 8 publications

Immunohistochemistry (IHC)

-

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

-

Immunocytochemistry (ICC/IF)

1:20-1:200

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SPRR3 Fusion Protein Ag2337 (1-161 aa encoded by BC017802)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.17 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MSSYQQKQT FTPPPQLQQQ QVKQPSQPPP QEIFVPTTKE PCHSKVPQPG NTKIPEPGCT KVPEPGCTKV PEPGCTKVPE PGCTKVPEPG CTKVPEPGYT KVPEPGSIKV PDQGFIKFPE PGAIKVPEQG YTKVPVPGYT KVPEPCPSTV TPGPAQQKTK QK (1-161 aa encoded by BC017802)

Target Information

SPRR3 is the cross-linked envelope protein of keratinocytes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Discovery of novel microRNA mimic repressors of ribosome biogenesis.

bioRxiv : the preprint server for biology

Bryant CJ,McCool MA,Rosado-González GT,Abriola L,Surovtseva YV,Baserga SJ

Tue Oct 10 00:00:00 EDT 2023

Investigation of mouse amniotic fluid for stimulating ability of keratinocyte differentiation depending on the fetal stage.

Archives of biochemistry and biophysics

Kuribayashi M,Kawaguchi Y,Teshima H,Yamaguchi H,Tatsukawa H,Hitomi K

Sat Oct 30 00:00:00 EDT 2021

Dysregulation of SPRR3/miR-876-3p Axis Contributes to Tumorigenesis in Non-Small-Cell Lung Cancer.

OncoTargets and therapy

Li Q,Wang Y,Hu R,Yang G

Wed Apr 13 00:00:00 EDT 2022

Small proline-rich repeat 3 is a novel coordinator of PDGFRβ and integrin β1 crosstalk to augment proliferation and matrix synthesis by cardiac fibroblasts.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Saraswati S,Lietman CD,Li B,Mathew S,Zent R,Young PP

Mon Jun 01 00:00:00 EDT 2020

Small proline-rich repeat 3 is a novel coordinator of PDGFRβ and integrin β1 crosstalk to augment proliferation and matrix synthesis by cardiac fibroblasts.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Saraswati S,Lietman CD,Li B,Mathew S,Zent R,Young PP

Mon Jun 01 00:00:00 EDT 2020

Small proline-rich repeat 3 is a novel coordinator of PDGFRβ and integrin β1 crosstalk to augment proliferation and matrix synthesis by cardiac fibroblasts.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Saraswati S,Lietman CD,Li B,Mathew S,Zent R,Young PP

Mon Jun 01 00:00:00 EDT 2020

Small proline-rich repeat 3 is a novel coordinator of PDGFRβ and integrin β1 crosstalk to augment proliferation and matrix synthesis by cardiac fibroblasts.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Saraswati S,Lietman CD,Li B,Mathew S,Zent R,Young PP

Mon Jun 01 00:00:00 EDT 2020

Small proline-rich repeat 3 is a novel coordinator of PDGFRβ and integrin β1 crosstalk to augment proliferation and matrix synthesis by cardiac fibroblasts.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Saraswati S,Lietman CD,Li B,Mathew S,Zent R,Young PP

Mon Jun 01 00:00:00 EDT 2020

Small proline-rich repeat 3 is a novel coordinator of PDGFRβ and integrin β1 crosstalk to augment proliferation and matrix synthesis by cardiac fibroblasts.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Saraswati S,Lietman CD,Li B,Mathew S,Zent R,Young PP

Mon Jun 01 00:00:00 EDT 2020

Fine particulate matter (PM2.5) inhibits ciliogenesis by increasing SPRR3 expression via c-Jun activation in RPE cells and skin keratinocytes.

Scientific reports

Bae JE,Choi H,Shin DW,Na HW,Park NY,Kim JB,Jo DS,Cho MJ,Lyu JH,Chang JH,Lee EH,Lee TR,Kim HJ,Cho DH

Fri Mar 08 00:00:00 EST 2019

Fine particulate matter (PM2.5) inhibits ciliogenesis by increasing SPRR3 expression via c-Jun activation in RPE cells and skin keratinocytes.

Scientific reports

Bae JE,Choi H,Shin DW,Na HW,Park NY,Kim JB,Jo DS,Cho MJ,Lyu JH,Chang JH,Lee EH,Lee TR,Kim HJ,Cho DH

Fri Mar 08 00:00:00 EST 2019

Studies on differentiation-dependent expression and activity of distinct transglutaminases by specific substrate peptides using three-dimensional reconstituted epidermis.

The FEBS journal

Tanabe Y,Yamane M,Kato M,Teshima H,Kuribayashi M,Tatsukawa H,Takama H,Akiyama M,Hitomi K

Mon Jul 01 00:00:00 EDT 2019

Expression of SPRR3 is associated with tumor cell proliferation in less advanced stages of breast cancer.

Breast cancer research and treatment

Kim JC,Yu JH,Cho YK,Jung CS,Ahn SH,Gong G,Kim YS,Cho DH

Fri Jun 01 00:00:00 EDT 2012

Expression of SPRR3 is associated with tumor cell proliferation in less advanced stages of breast cancer.

Breast cancer research and treatment

Kim JC,Yu JH,Cho YK,Jung CS,Ahn SH,Gong G,Kim YS,Cho DH

Fri Jun 01 00:00:00 EDT 2012

Expression of SPRR3 is associated with tumor cell proliferation in less advanced stages of breast cancer.

Breast cancer research and treatment

Kim JC,Yu JH,Cho YK,Jung CS,Ahn SH,Gong G,Kim YS,Cho DH

Fri Jun 01 00:00:00 EDT 2012

Expression of SPRR3 is associated with tumor cell proliferation in less advanced stages of breast cancer.

Breast cancer research and treatment

Kim JC,Yu JH,Cho YK,Jung CS,Ahn SH,Gong G,Kim YS,Cho DH

Fri Jun 01 00:00:00 EDT 2012

Upregulation of SPRR3 promotes colorectal tumorigenesis.

Molecular medicine (Cambridge, Mass.)

Cho DH,Jo YK,Roh SA,Na YS,Kim TW,Jang SJ,Kim YS,Kim JC

Mon Nov 08 00:00:00 EST 2010

Upregulation of SPRR3 promotes colorectal tumorigenesis.

Molecular medicine (Cambridge, Mass.)

Cho DH,Jo YK,Roh SA,Na YS,Kim TW,Jang SJ,Kim YS,Kim JC

Mon Nov 08 00:00:00 EST 2010

Upregulation of SPRR3 promotes colorectal tumorigenesis.

Molecular medicine (Cambridge, Mass.)

Cho DH,Jo YK,Roh SA,Na YS,Kim TW,Jang SJ,Kim YS,Kim JC

Mon Nov 08 00:00:00 EST 2010

Upregulation of SPRR3 promotes colorectal tumorigenesis.

Molecular medicine (Cambridge, Mass.)

Cho DH,Jo YK,Roh SA,Na YS,Kim TW,Jang SJ,Kim YS,Kim JC

Mon Nov 08 00:00:00 EST 2010

Bioinformatics

Protein Aliases: 22 kDa pancornulin; Cornifin beta; Esophagin; Small proline-rich protein 3

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Gene Aliases: SPRC; SPRR3

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UniProt ID: (Human) Q9UBC9

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Entrez Gene ID: (Human) 6707

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structural molecule activity protein binding

Process(es)

epidermis development peptide cross-linking keratinocyte differentiation keratinization wound healing

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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