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            • Primary Antibodies ›
            • SPTB Antibodies

            Invitrogen

            SPTB Polyclonal Antibody

            Advanced Verification
            View all (12) SPTB antibodies
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            Cite SPTB Polyclonal Antibody

            • Antibody Testing Data (3)
            • Advanced Verification (1)
            Application
            SPTB Antibody in Immunocytochemistry (ICC/IF)
            Group 53 Created with Sketch.

            FIGURE: 1 / 4

            SPTB Antibody (PA5-82088) in ICC/IF

            Immunofluorecent analysis of SPTB in human cell line U-2 OS using SPTB Polyclonal Antibody (Product # PA5-82088). Staining shows localization to cytosol.
            View Product

            SPTB Antibody in Immunocytochemistry (ICC/IF)
            SPTB Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            SPTB Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            SPTB Antibody

            Product Details

            PA5-82088

            Applications
            Tested Dilution
            Publications

            Immunohistochemistry (Paraffin) (IHC (P))

            1:500-1:1,000
            -

            Immunocytochemistry (ICC/IF)

            0.25-2 µg/mL
            -
            Product Specifications

            Species Reactivity

            Human

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Recombinant protein corresponding to Human SPTB. Recombinant protein control fragment (Product #RP-89116).

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            0.4 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            PBS, pH 7.2, with 40% glycerol

            Contains

            0.02% sodium azide

            Storage conditions

            Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_2789249

            Product Specific Information

            Immunogen sequence: TSVLILQRKH KAFEDELRGL DAHLEQIFQE AHGMVARKQF GHPQIEARIK EVSAQWDQLK DLAAFCKKNL QDAENFFQFQ GDADDLKAWL QDAHRLLSGE DVGQDEGATR ALGKKHKDFL EELEESRGVM EHLEQQAQGF PEEF

            Target Information

            SPTB (Spectrin Beta, Erythrocytic) is a Protein Coding gene. Diseases associated with SPTB include Spherocytosis, Type 2 and Elliptocytosis 3. Among its related pathways are Cytokine Signaling in Immune system and RET signaling. Gene Ontology (GO) annotations related to this gene include protein heterodimerization activity and actin filament binding. An important paralog of this gene is SPTBN1.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: Beta-I spectrin; HSPTB1; membrane cytoskeletal protein; Sp beta; spectrin beta chain, erythrocyte; Spectrin beta chain, erythrocytic; Spectrin Beta Erythrocytic; spectrin beta Tandil; Spectrin Beta, Erythrocytic; SPTB1

            View more View less

            Gene Aliases: EL3; HS2; HSPTB1; SPH2; SPTB; SPTB1

            View more View less

            UniProt ID: (Human) P11277

            View more View less

            Entrez Gene ID: (Human) 6710

            View more View less

            Function(s)

            actin binding Ras guanyl-nucleotide exchange factor activity structural constituent of cytoskeleton protein binding ankyrin binding actin filament binding

            Process(es)

            MAPK cascade ER to Golgi vesicle-mediated transport cytoskeleton organization axon guidance positive regulation of GTPase activity actin filament capping
            It has to be done as per old AB suggested Products section.
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            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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