Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MSTPSRFKK DKEIIAEYES QVKEIRAQLV EQQKCLEQQT EMRVQLLQDL QDFFRKKAEI ETEYSRNLEK LAERFMAKTR STKDHQQYKK DQNLLSPVNC WYLLLNQVRR ESKDHATLSD IYLNNVIMRF MQISEDSTRM FKKSKEIAFQ LHEDLMKVLN ELYTVMKTYH MYHAESISAE SKLKEAEKQE EKQIGRSGDP VFHIRLEERH QRRSSVKKIE KMKEKRQAKY SENKLKSIKA RNEYLLTLEA TNASVFKYYI HDLSDLIDCC DLGYHASLNR ALRTYLSAEY NLETSRHEGL D (1-300 aa encoded by BC029919)
The protein encoded by this gene is a GTPase activator, working with the GTPase CDC42 to negatively regulate neuronal migration. The encoded protein interacts with the transmembrane receptor ROBO1 to inactivate CDC42.
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Protein Aliases: Rho GTPase activating protein 13; Rho GTPase-activating protein 13; SLIT-ROBO Rho GTPase-activating protein 1; srGAP1
Gene Aliases: 4930572H05Rik; ARHGAP13; KIAA1304; NMTC2; RGD1566260; SRGAP1
UniProt ID: (Human) Q7Z6B7, (Mouse) Q91Z69
Entrez Gene ID: (Human) 57522, (Rat) 314903, (Mouse) 117600
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