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            • Primary Antibodies ›
            • SRGAP2 Antibodies

            Invitrogen

            SRGAP2 Polyclonal Antibody

            View all (7) SRGAP2 antibodies
            Datasheet
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            Datasheet
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            Questions & Answers

            Cite SRGAP2 Polyclonal Antibody

            • Antibody Testing Data (1)
            Application
            SRGAP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Group 53 Created with Sketch.

            FIGURE: 1 / 1

            SRGAP2 Antibody (PA5-50888) in IHC (P)

            Immunohistochemical analysis of SRGAP2 in paraffin embedded Human liver cancer tissue using SRGAP2 Polyclonal Antibody (Product # PA5-50888) at a 1:20 dilution.
            View Product

            SRGAP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

            Product Details

            PA5-50888

            Applications
            Tested Dilution
            Publications

            Immunohistochemistry (Paraffin) (IHC (P))

            1:25-1:100
            -
            Product Specifications

            Species Reactivity

            Human, Mouse, Rat

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Synthetic peptide corresponding to a region derived from internal residues of human SLIT-ROBO Rho GTPase activating protein 2

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            1.3 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            PBS, pH 7.4, with 40% glycerol

            Contains

            0.05% sodium azide

            Storage conditions

            -20°C

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_2636340

            Product Specific Information

            The antibody detects endogenous levels of total SRGAP2 protein.

            Target Information

            This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: FBP-27; formin binding protein 2; Formin-binding protein 2; Formin-binding protein 27; Rho GTPase-activating protein 34; SLIT-ROBO GAP2; SLIT-ROBO Rho GTPase-activating protein 2; srGAP2

            View more View less

            Gene Aliases: 9930124L22Rik; AI448945; ARHGAP34; FBP2; Fbp27; FNBP2; KIAA0456; RGD1566016; SRGAP2; SRGAP2A; SRGAP3

            View more View less

            UniProt ID: (Human) O75044, (Rat) D4A208, (Mouse) Q91Z67

            View more View less

            Entrez Gene ID: (Human) 23380, (Rat) 360840, (Mouse) 14270

            View more View less

            Function(s)

            GTPase activator activity protein binding protein homodimerization activity Rac GTPase binding GTPase-activating protein

            Process(es)

            lamellipodium assembly involved in ameboidal cell migration signal transduction cell proliferation extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration substrate adhesion-dependent cell spreading positive regulation of GTPase activity filopodium assembly neuron projection morphogenesis actin filament severing regulation of small GTPase mediated signal transduction negative regulation of cell death dendritic spine development negative regulation of neuron migration negative regulation of cell migration nervous system development
            It has to be done as per old AB suggested Products section.
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            Performance Guarantee

            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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