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SRPK1 is a serine/threonine kinase that plays a role in the regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. SRPK1 localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. A second alternatively spliced transcript variant for this gene has been described, but its full length nature has not been determined.
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Protein Aliases: OTTHUMP00000016277; serine/arginine-rich protein specific kinase 1; Serine/arginine-rich protein-specific kinase 1; serine/arginine-rich splicing factor kinase 1; serine/threonine-protein kinase SRPK1; SFRS protein kinase 1; SR protein-specific kinase 1; SR-protein-specific kinase 1; SRPK1; SRSF protein kinase 1
Gene Aliases: AU017960; SFRSK1; SRPK1
UniProt ID: (Human) Q96SB4, (Mouse) O70551
Entrez Gene ID: (Human) 6732, (Mouse) 20815, (Rat) 361811
Molecular Function:
non-receptor serine/threonine protein kinase
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