Product References
Splicing regulation of GFPT1 muscle-specific isoform and its roles in glucose metabolisms and neuromuscular junction.
iScience
Farshadyeganeh P,Nazim M,Zhang R,Ohkawara B,Nakajima K,Rahman MA,Nasrin F,Ito M,Takeda JI,Ohe K,Miyasaka Y,Ohno T,Masuda A,Ohno K
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Fri Oct 20 00:00:00 UTC 2023
PI3Kα Translocation Mediates Nuclear PtdIns(3,4,5)P3 Effector Signaling in Colorectal Cancer.
Molecular & cellular proteomics : MCP
Palmieri M,Catimel B,Mouradov D,Sakthianandeswaren A,Kapp E,Ang CS,Williamson NA,Nowell CJ,Christie M,Desai J,Gibbs P,Burgess AW,Sieber OM
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Sat Apr 01 00:00:00 UTC 2023
N6-Methyladenosine Methyltransferase METTL3 Alleviates Diabetes-Induced Testicular Damage through Modulating TUG1/Clusterin Axis.
Diabetes & metabolism journal
Tian Y,Xiao YH,Sun C,Liu B,Sun F
32-4500 was used in RNA Immunoprecipitation to elucidate the potential regulatory mechanisms of m6A modification on diabetes-induced testicular injury.
Wed Mar 01 00:00:00 UTC 2023
Antecedent chromatin organization determines cGAS recruitment to ruptured micronuclei.
Nature communications
MacDonald KM,Nicholson-Puthenveedu S,Tageldein MM,Khasnis S,Arrowsmith CH,Harding SM
32-4500 was used in Western Blotting to define micronuclei as integrative signaling hubs for the cellular response to genotoxic stress.
Thu Feb 02 00:00:00 UTC 2023
SRSF1 acts as an IFN-I-regulated cellular dependency factor decisively affecting HIV-1 post-integration steps.
Frontiers in immunology
Sertznig H,Roesmann F,Wilhelm A,Heininger D,Bleekmann B,Elsner C,Santiago M,Schuhenn J,Karakoese Z,Benatzy Y,Snodgrass R,Esser S,Sutter K,Dittmer U,Widera M
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Mon Dec 05 00:00:00 UTC 2022
Tissue-specific alternative splicing separates the catalytic and cell signaling functions of human leucyl-tRNA synthetase.
The Journal of biological chemistry
Baymiller M,Nordick B,Forsyth CM,Martinis SA
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Fri Apr 01 00:00:00 UTC 2022
Tissue-specific alternative splicing separates the catalytic and cell signaling functions of human leucyl-tRNA synthetase.
The Journal of biological chemistry
Baymiller M,Nordick B,Forsyth CM,Martinis SA
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Fri Apr 01 00:00:00 UTC 2022
FOXA1 regulates alternative splicing in prostate cancer.
Cell reports
Del Giudice M,Foster JG,Peirone S,Rissone A,Caizzi L,Gaudino F,Parlato C,Anselmi F,Arkell R,Guarrera S,Oliviero S,Basso G,Rajan P,Cereda M
32-4500 was used in Western Blotting to investigate FOXA1 on the transcriptional programs in prostate cancer.
Tue Sep 27 00:00:00 UTC 2022
Antisense Oligonucleotide Rescue of Deep-Intronic Variants Activating Pseudoexons in the 6-Pyruvoyl-Tetrahydropterin Synthase Gene.
Nucleic acid therapeutics
Martínez-Pizarro A,Leal F,Holm LL,Doktor TK,Petersen USS,Bueno M,Thöny B,Pérez B,Andresen BS,Desviat LR
32-4500 was used in Western Blotting to report two new 6-pyruvoyl-tetrahydropterin synthase splicing variants identified through genomic sequencing and transcript analysis in a patient with tetrahydrobiopterin deficiency, presenting with hyperphenylalaninemia and monoamine neurotransmitter deficiency.
Sat Oct 01 00:00:00 UTC 2022
In-depth analysis of alternative splicing landscape in multiple myeloma and potential role of dysregulated splicing factors.
Blood cancer journal
Aktas Samur A,Fulciniti M,Avet-Loiseau H,Lopez MA,Derebail S,Corre J,Minvielle S,Magrangeas F,Moreau P,Anderson KC,Parmigiani G,Samur MK,Munshi NC
32-4500 was used in Western Blotting to develop a web portal that allows custom alternative splicing event queries by using gene symbols and visualizes AS events in MM and subgroups.
Tue Dec 20 00:00:00 UTC 2022
LINC00173 promotes Wilms' tumor progression through MGAT1-mediated MUC3A N-glycosylation.
Cell cycle (Georgetown, Tex.)
Zhu Q,Zhan D,Yang Y,Chong Y,Xue H,Zhu P
32-4500 was used in Immunoprecipitation to further understanding the mechanism underlying WT progression.
Thu Sep 01 00:00:00 UTC 2022
RBFOX2 alters splicing outcome in distinct binding modes with multiple protein partners.
Nucleic acids research
Zhou D,Couture S,Scott MS,Abou Elela S
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Immunoprecipitation
Fri Aug 20 00:00:00 UTC 2021
RBFOX2 alters splicing outcome in distinct binding modes with multiple protein partners.
Nucleic acids research
Zhou D,Couture S,Scott MS,Abou Elela S
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Immunoprecipitation
Fri Aug 20 00:00:00 UTC 2021
RBFOX2 alters splicing outcome in distinct binding modes with multiple protein partners.
Nucleic acids research
Zhou D,Couture S,Scott MS,Abou Elela S
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Immunoprecipitation
Fri Aug 20 00:00:00 UTC 2021
Disruption of exon-bridging interactions between the minor and major spliceosomes results in alternative splicing around minor introns.
Nucleic acids research
Olthof AM,White AK,Mieruszynski S,Doggett K,Lee MF,Chakroun A,Abdel Aleem AK,Rousseau J,Magnani C,Roifman CM,Campeau PM,Heath JK,Kanadia RN
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Tue Apr 06 00:00:00 UTC 2021
Disruption of exon-bridging interactions between the minor and major spliceosomes results in alternative splicing around minor introns.
Nucleic acids research
Olthof AM,White AK,Mieruszynski S,Doggett K,Lee MF,Chakroun A,Abdel Aleem AK,Rousseau J,Magnani C,Roifman CM,Campeau PM,Heath JK,Kanadia RN
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Tue Apr 06 00:00:00 UTC 2021
Splicing factor SRSF1 limits IFN-γ production via RhoH and ameliorates experimental nephritis.
Rheumatology (Oxford, England)
Katsuyama T,Li H,Krishfield SM,Kyttaris VC,Moulton VR
32-4500 was used in Western Blot to uncover a previously unrecognized role of SRSF1 in restraining IFN-γ production and Th1 differentiation through the control of RhoH.
Tue Jan 05 00:00:00 UTC 2021
Overexpression of hsa_circ_0001445 reverses oxLDL‑induced inhibition of HUVEC proliferation via SRSF1.
Molecular medicine reports
Liang G,Chen S,Xin S,Dong L
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Thu Jul 01 00:00:00 UTC 2021
Overexpression of hsa_circ_0001445 reverses oxLDL‑induced inhibition of HUVEC proliferation via SRSF1.
Molecular medicine reports
Liang G,Chen S,Xin S,Dong L
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Thu Jul 01 00:00:00 UTC 2021
The effect of splicing MST1R in gastric cancer was enhanced by lncRNA FENDRR.
Experimental and therapeutic medicine
Zhou D,Zhu X,Wu X,Zheng J,Tou L,Zhou Y
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Sun Aug 01 00:00:00 UTC 2021
The effect of splicing MST1R in gastric cancer was enhanced by lncRNA FENDRR.
Experimental and therapeutic medicine
Zhou D,Zhu X,Wu X,Zheng J,Tou L,Zhou Y
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Sun Aug 01 00:00:00 UTC 2021
The Thiazole-5-Carboxamide GPS491 Inhibits HIV-1, Adenovirus, and Coronavirus Replication by Altering RNA Processing/Accumulation.
Viruses
Dahal S,Cheng R,Cheung PK,Been T,Malty R,Geng M,Manianis S,Shkreta L,Jahanshahi S,Toutant J,Chan R,Park S,Brockman MA,Babu M,Mubareka S,Mossman K,Banerjee A,Gray-Owen S,Brown M,Houry WA,Chabot B,Grierson D,Cochrane A
32-4500 was used in Western Blot to establish that a compound that impacts the activity of cellular factors involved in RNA processing can prevent the replication of several viruses with minimal effect on cell viability.
Thu Dec 30 00:00:00 UTC 2021
FGF-2 promotes angiogenesis through a SRSF1/SRSF3/SRPK1-dependent axis that controls VEGFR1 splicing in endothelial cells.
BMC biology
Jia T,Jacquet T,Dalonneau F,Coudert P,Vaganay E,Exbrayat-Héritier C,Vollaire J,Josserand V,Ruggiero F,Coll JL,Eymin B
32-4500 was used in Western Blot to demonstrate that FGF-2 promotes angiogenesis by activating a SRSF1/SRSF3/SRPK1 network that regulates VEGFR1 alternative splicing in endothelial cells, a process that could also contribute to lung tumor progression.
Wed Aug 25 00:00:00 UTC 2021
Hallmarks and Determinants of Oncogenic Translation Revealed by Ribosome Profiling in Models of Breast Cancer.
Translational oncology
Vaklavas C,Blume SW,Grizzle WE
32-4500 was used in Immunoprecipitation, Immunocytochemsitry, and RNA Immunoprecipitation to analyze translation in cell line models of breast cancer and normal mammary tissue by ribosome profiling.
Sat Feb 01 00:00:00 UTC 2020
Hallmarks and Determinants of Oncogenic Translation Revealed by Ribosome Profiling in Models of Breast Cancer.
Translational oncology
Vaklavas C,Blume SW,Grizzle WE
32-4500 was used in Immunoprecipitation, Immunocytochemsitry, and RNA Immunoprecipitation to analyze translation in cell line models of breast cancer and normal mammary tissue by ribosome profiling.
Sat Feb 01 00:00:00 UTC 2020
Hallmarks and Determinants of Oncogenic Translation Revealed by Ribosome Profiling in Models of Breast Cancer.
Translational oncology
Vaklavas C,Blume SW,Grizzle WE
32-4500 was used in Immunoprecipitation, Immunocytochemsitry, and RNA Immunoprecipitation to analyze translation in cell line models of breast cancer and normal mammary tissue by ribosome profiling.
Sat Feb 01 00:00:00 UTC 2020
Hallmarks and Determinants of Oncogenic Translation Revealed by Ribosome Profiling in Models of Breast Cancer.
Translational oncology
Vaklavas C,Blume SW,Grizzle WE
32-4500 was used in Immunoprecipitation, Immunocytochemsitry, and RNA Immunoprecipitation to analyze translation in cell line models of breast cancer and normal mammary tissue by ribosome profiling.
Sat Feb 01 00:00:00 UTC 2020
First Identification of RNA-Binding Proteins That Regulate Alternative Exons in the Dystrophin Gene.
International journal of molecular sciences
Miro J,Bougé AL,Murauer E,Beyne E,Da Cunha D,Claustres M,Koenig M,Tuffery-Giraud S
32-4500 was used in Western Blotting to identify RNA-binding proteins (RBPs) that regulate splicing of its skeletal muscle isoform (Dp427m) in a human muscular cell line, usingan RNAi-based approach coupled with DMD-targeted RNA-seq.
Wed Oct 21 00:00:00 UTC 2020
An activator of G protein-coupled receptor and MEK1/2-ERK1/2 signaling inhibits HIV-1 replication by altering viral RNA processing.
PLoS pathogens
Wong RW,Balachandran A,Cheung PK,Cheng R,Pan Q,Stoilov P,Harrigan PR,Blencowe BJ,Branch DR,Cochrane A
32-4500 was used in Western Blot to demonstrate enhanced sensitivity of HIV-1 gene expression to small changes in host RNA processing and highlights the potential of modulating host intracellular signaling as an alternative approach for controlling HIV-1 infection.
Sat Feb 01 00:00:00 UTC 2020
Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation.
Nature communications
Sajini AA,Choudhury NR,Wagner RE,Bornelöv S,Selmi T,Spanos C,Dietmann S,Rappsilber J,Michlewski G,Frye M
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Tue Jun 11 00:00:00 UTC 2019
Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation.
Nature communications
Sajini AA,Choudhury NR,Wagner RE,Bornelöv S,Selmi T,Spanos C,Dietmann S,Rappsilber J,Michlewski G,Frye M
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Tue Jun 11 00:00:00 UTC 2019
hnRNPK promotes gastric tumorigenesis through regulating CD44E alternative splicing.
Cancer cell international
Peng WZ,Liu JX,Li CF,Ma R,Jie JZ
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Mon Apr 11 00:00:00 UTC 2022
Enhanced osteopontin splicing regulated by RUNX2 is HDAC-dependent and induces invasive phenotypes in NSCLC cells.
Cancer cell international
Huang J,Chang S,Lu Y,Wang J,Si Y,Zhang L,Cheng S,Jiang WG
32-4500 was used in Western Blotting to suggest the increase of minor splicing variant of OPNc required both (1) the enhanced transcription from its coding gene driven by specific transcription factors; and (2) the simultaneous modulation or fluctuation of the coupled splicing process that depends to selective classed of epigenetic regulators, predominately HDAC family members.
Mon Apr 11 00:00:00 UTC 2022
Biological and RNA regulatory function of MOV10 in mammalian germ cells.
BMC biology
Fu K,Tian S,Tan H,Wang C,Wang H,Wang M,Wang Y,Chen Z,Wang Y,Yue Q,Xu Q,Zhang S,Li H,Xie J,Lin M,Luo M,Chen F,Ye L,Zheng K
32-4500 was used in Western Blotting to expand the landscape of MOV10 function and highlight a previously unidentified role initiated from the nucleus, suggesting that MOV10 is a versatile RBP involved in a broader RNA regulatory network.
Tue May 14 00:00:00 UTC 2019
Effects of SRSF1 on subnuclear localization of topoisomerase I.
Journal of cellular biochemistry
Girstun A,Ishikawa T,Staron K
32-4500 was used in Western Blotting to suggest a possible role of SRSF1 in establishing partition of top I between the nucleolus and the nucleoplasm in some cell types with distinct combinations of SR proteins levels.
Mon Jul 01 00:00:00 UTC 2019
Intronic PAH gene mutations cause a splicing defect by a novel mechanism involving U1snRNP binding downstream of the 5' splice site.
PLoS genetics
Martínez-Pizarro A,Dembic M,Pérez B,Andresen BS,Desviat LR
32-4500 was used in Western Blotting to indicate that U1snRNP binding downstream of the natural 5' splice site determines efficient exon 11 splicing.
Sun Apr 01 00:00:00 UTC 2018
DAZL Regulates Germ Cell Survival through a Network of PolyA-Proximal mRNA Interactions.
Cell reports
Zagore LL,Sweet TJ,Hannigan MM,Weyn-Vanhentenryck SM,Jobava R,Hatzoglou M,Zhang C,Licatalosi DD
32-4500 was used in Immunoprecipitation to reveal a mechanism for DAZL-RNA binding and illustrate that DAZL functions as a master regulator of a post-transcriptional mRNA program essential for germ cell survival.
Tue Oct 30 00:00:00 UTC 2018
Integrated Molecular Characterization of Uterine Carcinosarcoma.
Cancer cell
Cherniack AD,Shen H,Walter V,Stewart C,Murray BA,Bowlby R,Hu X,Ling S,Soslow RA,Broaddus RR,Zuna RE,Robertson G,Laird PW,Kucherlapati R,Mills GB,Weinstein JN,Zhang J,Akbani R,Levine DA
324500 was used in reverse phase protein array to characterize the molecular identity of uterine carcinosarcomas.
Mon Mar 13 00:00:00 UTC 2017
Succession of splicing regulatory elements determines cryptic 5΄ss functionality.
Nucleic acids research
Brillen AL,Schöneweis K,Walotka L,Hartmann L,Müller L,Ptok J,Kaisers W,Poschmann G,Stühler K,Buratti E,Theiss S,Schaal H
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Thu Apr 20 00:00:00 UTC 2017
Succession of splicing regulatory elements determines cryptic 5΄ss functionality.
Nucleic acids research
Brillen AL,Schöneweis K,Walotka L,Hartmann L,Müller L,Ptok J,Kaisers W,Poschmann G,Stühler K,Buratti E,Theiss S,Schaal H
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Thu Apr 20 00:00:00 UTC 2017
SRSF1 promotes vascular smooth muscle cell proliferation through a Δ133p53/EGR1/KLF5 pathway.
Nature communications
Xie N,Chen M,Dai R,Zhang Y,Zhao H,Song Z,Zhang L,Li Z,Feng Y,Gao H,Wang L,Zhang T,Xiao RP,Wu J,Cao CM
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Fri Aug 11 00:00:00 UTC 2017
SRSF1 suppresses selection of intron-distal 5' splice site of DOK7 intron 4 to generate functional full-length Dok-7 protein.
Scientific reports
Ahsan KB,Masuda A,Rahman MA,Takeda JI,Nazim M,Ohkawara B,Ito M,Ohno K
32-4500 was used in Western Blotting to demonstrate that SRSF1 critically regulates alternative selection of adjacently placed 5' splice sites by modulating binding of U1 snRNP.
Tue Sep 05 00:00:00 UTC 2017
SRSF1 suppresses selection of intron-distal 5' splice site of DOK7 intron 4 to generate functional full-length Dok-7 protein.
Scientific reports
Ahsan KB,Masuda A,Rahman MA,Takeda JI,Nazim M,Ohkawara B,Ito M,Ohno K
32-4500 was used in Western Blotting to demonstrate that SRSF1 critically regulates alternative selection of adjacently placed 5' splice sites by modulating binding of U1 snRNP.
Tue Sep 05 00:00:00 UTC 2017
A genome landscape of SRSF3-regulated splicing events and gene expression in human osteosarcoma U2OS cells.
Nucleic acids research
Ajiro M,Jia R,Yang Y,Zhu J,Zheng ZM
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Mon Feb 29 00:00:00 UTC 2016
A genome landscape of SRSF3-regulated splicing events and gene expression in human osteosarcoma U2OS cells.
Nucleic acids research
Ajiro M,Jia R,Yang Y,Zhu J,Zheng ZM
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Mon Feb 29 00:00:00 UTC 2016
The alternative splicing program of differentiated smooth muscle cells involves concerted non-productive splicing of post-transcriptional regulators.
Nucleic acids research
Llorian M,Gooding C,Bellora N,Hallegger M,Buckroyd A,Wang X,Rajgor D,Kayikci M,Feltham J,Ule J,Eyras E,Smith CW
32-4500 was used in western blot to characterize the involvement of concerted non-productive splicing of post-transcriptional regulators that involves the alternative splicing program of differentiatied smooth muscle cells
Fri Oct 14 00:00:00 UTC 2016
Human Papillomavirus E2 Regulates SRSF3 (SRp20) To Promote Capsid Protein Expression in Infected Differentiated Keratinocytes.
Journal of virology
Klymenko T,Hernandez-Lopez H,MacDonald AI,Bodily JM,Graham SV
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Sun May 15 00:00:00 UTC 2016
Serine/Arginine-Rich Splicing Factor 3 and Heterogeneous Nuclear Ribonucleoprotein A1 Regulate Alternative RNA Splicing and Gene Expression of Human Papillomavirus 18 through Two Functionally Distinguishable cis Elements.
Journal of virology
Ajiro M,Tang S,Doorbar J,Zheng ZM
324500 was used in western blot to investigate alternative RNA splicing of HPV18 pre-mRNAs
Sat Oct 15 00:00:00 UTC 2016
Rescue of Isolated GH Deficiency Type II (IGHD II) via Pharmacologic Modulation of GH-1 Splicing.
Endocrinology
Miletta MC,Petkovic V,Eblé A,Flück CE,Mullis PE
32-4500 was used in western blot to research pharmacologic modulation of GH-1 splicing due to rescue of isolated growth hormone deficiency type II (IGHD II)
Sat Oct 01 00:00:00 UTC 2016
Splice-shifting oligonucleotide (SSO) mediated blocking of an exonic splicing enhancer (ESE) created by the prevalent c.903+469T>C MTRR mutation corrects splicing and restores enzyme activity in patient cells.
Nucleic acids research
Palhais B,Præstegaard VS,Sabaratnam R,Doktor TK,Lutz S,Burda P,Suormala T,Baumgartner M,Fowler B,Bruun GH,Andersen HS,Kožich V,Andresen BS
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Tue May 19 00:00:00 UTC 2015
Human Papillomavirus 16 Oncoprotein Expression Is Controlled by the Cellular Splicing Factor SRSF2 (SC35).
Journal of virology
McFarlane M,MacDonald AI,Stevenson A,Graham SV
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Fri May 01 00:00:00 UTC 2015
SRSF1 and hnRNP H antagonistically regulate splicing of COLQ exon 16 in a congenital myasthenic syndrome.
Scientific reports
Rahman MA,Azuma Y,Nasrin F,Takeda J,Nazim M,Bin Ahsan K,Masuda A,Engel AG,Ohno K
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Tue Aug 18 00:00:00 UTC 2015
Identification by high-throughput imaging of the histone methyltransferase EHMT2 as an epigenetic regulator of VEGFA alternative splicing.
Nucleic acids research
Salton M,Voss TC,Misteli T
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in ChIP assay
Tue Dec 16 00:00:00 UTC 2014
Identification by high-throughput imaging of the histone methyltransferase EHMT2 as an epigenetic regulator of VEGFA alternative splicing.
Nucleic acids research
Salton M,Voss TC,Misteli T
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in ChIP assay
Tue Dec 16 00:00:00 UTC 2014
Alanine repeats influence protein localization in splicing speckles and paraspeckles.
Nucleic acids research
Chang SH,Chang WL,Lu CC,Tarn WY
32-4500 was used in ChIP assay to investigate the function of the alanine repeat-containing C-terminal domain of RNA-binding motif protein 4
Tue Dec 16 00:00:00 UTC 2014
Attenuation of the suppressive activity of cellular splicing factor SRSF3 by Kaposi sarcoma-associated herpesvirus ORF57 protein is required for RNA splicing.
RNA (New York, N.Y.)
Majerciak V,Lu M,Li X,Zheng ZM
32-4500 was used in western blot to study Kaposi sarcoma-associated herpesvirus ORF57 protein attenuates the suppressive activity of cellular splicing factor SRSF3 and is required by RNA splicing
Sat Nov 01 00:00:00 UTC 2014
Absence of an intron splicing silencer in porcine Smn1 intron 7 confers immunity to the exon skipping mutation in human SMN2.
PloS one
Doktor TK,Schrøder LD,Andersen HS,Brøner S,Kitewska A,Sørensen CB,Andresen BS
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Wed Aug 05 00:00:00 UTC 2015
SR proteins collaborate with 7SK and promoter-associated nascent RNA to release paused polymerase.
Cell
Ji X,Zhou Y,Pandit S,Huang J,Li H,Lin CY,Xiao R,Burge CB,Fu XD
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in ChIP assay
Thu May 09 00:00:00 UTC 2013
HnRNP A1 controls a splicing regulatory circuit promoting mesenchymal-to-epithelial transition.
Nucleic acids research
Bonomi S,di Matteo A,Buratti E,Cabianca DS,Baralle FE,Ghigna C,Biamonti G
32-4500 was used in Western Blotting to study how splicing regulation contributes to tumour progression and reveal potential targets to develop anticancer therapies.
Tue Oct 01 00:00:00 UTC 2013
Identification of the adenovirus E4orf4 protein binding site on the B55α and Cdc55 regulatory subunits of PP2A: Implications for PP2A function, tumor cell killing and viral replication.
PLoS pathogens
Mui MZ,Kucharski M,Miron MJ,Hur WS,Berghuis AM,Blanchette P,Branton PE
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Immunoprecipitation
Mon Jun 23 00:00:00 UTC 2014
Identification of the adenovirus E4orf4 protein binding site on the B55α and Cdc55 regulatory subunits of PP2A: Implications for PP2A function, tumor cell killing and viral replication.
PLoS pathogens
Mui MZ,Kucharski M,Miron MJ,Hur WS,Berghuis AM,Blanchette P,Branton PE
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Immunoprecipitation
Mon Jun 23 00:00:00 UTC 2014
A synonymous polymorphic variation in ACADM exon 11 affects splicing efficiency and may affect fatty acid oxidation.
Molecular genetics and metabolism
Bruun GH,Doktor TK,Andresen BS
32-4500 was used in western blot to study a single-nucleotide polymorphism, rs278C to T, located far upstream of the MCAD gene.
Mon Mar 17 00:00:00 UTC 2014
Paraquat modulates alternative pre-mRNA splicing by modifying the intracellular distribution of SRPK2.
PloS one
Vivarelli S,Lenzken SC,Ruepp MD,Ranzini F,Maffioletti A,Alvarez R,Mühlemann O,Barabino SM
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Thu Nov 14 00:00:00 UTC 2013
Paraquat modulates alternative pre-mRNA splicing by modifying the intracellular distribution of SRPK2.
PloS one
Vivarelli S,Lenzken SC,Ruepp MD,Ranzini F,Maffioletti A,Alvarez R,Mühlemann O,Barabino SM
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Thu Nov 14 00:00:00 UTC 2013
Eight nucleotide substitutions inhibit splicing to HPV-16 3'-splice site SA3358 and reduce the efficiency by which HPV-16 increases the life span of primary human keratinocytes.
PloS one
Li X,Johansson C,Cardoso Palacios C,Mossberg A,Dhanjal S,Bergvall M,Schwartz S
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Sun Jun 15 00:00:00 UTC 2014
Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing.
PLoS genetics
Pradeepa MM,Sutherland HG,Ule J,Grimes GR,Bickmore WA
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in ChIP assay
Wed Sep 26 00:00:00 UTC 2012
Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing.
PLoS genetics
Pradeepa MM,Sutherland HG,Ule J,Grimes GR,Bickmore WA
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in ChIP assay
Wed Sep 26 00:00:00 UTC 2012
Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing.
PLoS genetics
Pradeepa MM,Sutherland HG,Ule J,Grimes GR,Bickmore WA
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in ChIP assay
Wed Sep 26 00:00:00 UTC 2012
Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing.
PLoS genetics
Pradeepa MM,Sutherland HG,Ule J,Grimes GR,Bickmore WA
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in ChIP assay
Wed Sep 26 00:00:00 UTC 2012
A retroelement modifies pre-mRNA splicing: the murine Glrb(spa) allele is a splicing signal polymorphism amplified by long interspersed nuclear element insertion.
The Journal of biological chemistry
Becker K,Braune M,Benderska N,Buratti E,Baralle F,Villmann C,Stamm S,Eulenburg V,Becker CM
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Fri Sep 07 00:00:00 UTC 2012
A retroelement modifies pre-mRNA splicing: the murine Glrb(spa) allele is a splicing signal polymorphism amplified by long interspersed nuclear element insertion.
The Journal of biological chemistry
Becker K,Braune M,Benderska N,Buratti E,Baralle F,Villmann C,Stamm S,Eulenburg V,Becker CM
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Fri Sep 07 00:00:00 UTC 2012
Abnormal expression of the pre-mRNA splicing regulators SRSF1, SRSF2, SRPK1 and SRPK2 in non small cell lung carcinoma.
PloS one
Gout S,Brambilla E,Boudria A,Drissi R,Lantuejoul S,Gazzeri S,Eymin B
32-4500 was used in immunohistochemistry (paraffin) to study SRSF1 and SRSF2 in lung cancer.
Tue Apr 02 00:00:00 UTC 2013
Abnormal expression of the pre-mRNA splicing regulators SRSF1, SRSF2, SRPK1 and SRPK2 in non small cell lung carcinoma.
PloS one
Gout S,Brambilla E,Boudria A,Drissi R,Lantuejoul S,Gazzeri S,Eymin B
32-4500 was used in immunohistochemistry (paraffin) to study SRSF1 and SRSF2 in lung cancer.
Tue Apr 02 00:00:00 UTC 2013
Abnormal expression of the pre-mRNA splicing regulators SRSF1, SRSF2, SRPK1 and SRPK2 in non small cell lung carcinoma.
PloS one
Gout S,Brambilla E,Boudria A,Drissi R,Lantuejoul S,Gazzeri S,Eymin B
32-4500 was used in immunohistochemistry (paraffin) to study SRSF1 and SRSF2 in lung cancer.
Tue Apr 02 00:00:00 UTC 2013
Nucleocytoplasmic localization of p70 S6K1, but not of its isoforms p85 and p31, is regulated by TSC2/mTOR.
Oncogene
Rosner M,Hengstschläger M
32-4500 was used in Western Blotting to provide new important insights into the temporal and spatial dynamics of TSC2/mTOR/S6K regulation.
Thu Nov 03 00:00:00 UTC 2011
A conserved splicing mechanism of the LMNA gene controls premature aging.
Human molecular genetics
Lopez-Mejia IC,Vautrot V,De Toledo M,Behm-Ansmant I,Bourgeois CF,Navarro CL,Osorio FG,Freije JM,Stévenin J,De Sandre-Giovannoli A,Lopez-Otin C,Lévy N,Branlant C,Tazi J
Thu Dec 01 00:00:00 UTC 2011
Resveratrol, by modulating RNA processing factor levels, can influence the alternative splicing of pre-mRNAs.
PloS one
Markus MA,Marques FZ,Morris BJ
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Immunofluorescence
Mon Apr 23 00:00:00 UTC 2012
Resveratrol, by modulating RNA processing factor levels, can influence the alternative splicing of pre-mRNAs.
PloS one
Markus MA,Marques FZ,Morris BJ
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Immunofluorescence
Mon Apr 23 00:00:00 UTC 2012
Protein kinase a-dependent phosphorylation of serine 119 in the proto-oncogenic serine/arginine-rich splicing factor 1 modulates its activity as a splicing enhancer protein.
Genes & cancer
Aksaas AK,Eikvar S,Akusjärvi G,Skålhegg BS,Kvissel AK
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Immunoprecipitation
Mon Aug 01 00:00:00 UTC 2011
Protein kinase a-dependent phosphorylation of serine 119 in the proto-oncogenic serine/arginine-rich splicing factor 1 modulates its activity as a splicing enhancer protein.
Genes & cancer
Aksaas AK,Eikvar S,Akusjärvi G,Skålhegg BS,Kvissel AK
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Immunoprecipitation
Mon Aug 01 00:00:00 UTC 2011
Protein kinase a-dependent phosphorylation of serine 119 in the proto-oncogenic serine/arginine-rich splicing factor 1 modulates its activity as a splicing enhancer protein.
Genes & cancer
Aksaas AK,Eikvar S,Akusjärvi G,Skålhegg BS,Kvissel AK
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Immunoprecipitation
Mon Aug 01 00:00:00 UTC 2011
Disturbed expression of splicing factors in renal cancer affects alternative splicing of apoptosis regulators, oncogenes, and tumor suppressors.
PloS one
Piekielko-Witkowska A,Wiszomirska H,Wojcicka A,Poplawski P,Boguslawska J,Tanski Z,Nauman A
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Wed Oct 27 00:00:00 UTC 2010
Disturbed expression of splicing factors in renal cancer affects alternative splicing of apoptosis regulators, oncogenes, and tumor suppressors.
PloS one
Piekielko-Witkowska A,Wiszomirska H,Wojcicka A,Poplawski P,Boguslawska J,Tanski Z,Nauman A
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Wed Oct 27 00:00:00 UTC 2010
Coupled transcription-splicing regulation of mutually exclusive splicing events at the 5' exons of protein 4.1R gene.
Blood
Huang SC,Cho A,Norton S,Liu ES,Park J,Zhou A,Munagala ID,Ou AC,Yang G,Wickrema A,Tang TK,Benz EJ
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Thu Nov 05 00:00:00 UTC 2009
Coupled transcription-splicing regulation of mutually exclusive splicing events at the 5' exons of protein 4.1R gene.
Blood
Huang SC,Cho A,Norton S,Liu ES,Park J,Zhou A,Munagala ID,Ou AC,Yang G,Wickrema A,Tang TK,Benz EJ
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Thu Nov 05 00:00:00 UTC 2009
Coupled transcription-splicing regulation of mutually exclusive splicing events at the 5' exons of protein 4.1R gene.
Blood
Huang SC,Cho A,Norton S,Liu ES,Park J,Zhou A,Munagala ID,Ou AC,Yang G,Wickrema A,Tang TK,Benz EJ
Published figure using SRSF1 monoclonal antibody (Product # 32-4500) in Western Blot
Thu Nov 05 00:00:00 UTC 2009
The splicing factor SF2/ASF binds to ARS homologs in a human rDNA replication origin.
Cell cycle (Georgetown, Tex.)
He M,Shah D,Choung HY,Coffman FD
32-4500 was used in ChIP assay to investigate the mechanisms by which SF2/ASF contributes to oncogenesis
Sat Aug 15 00:00:00 UTC 2009
A novel role for PA28gamma-proteasome in nuclear speckle organization and SR protein trafficking.
Molecular biology of the cell
Baldin V,Militello M,Thomas Y,Doucet C,Fic W,Boireau S,Jariel-Encontre I,Piechaczyk M,Bertrand E,Tazi J,Coux O
32-4500 was used in Immunoprecipitation to identify proteasome-PA28gamma complexes as a novel regulator of nuclear speckles organization and function, acting most likely through selective proteolysis.
Tue Apr 01 00:00:00 UTC 2008
RNA splicing capability of live neuronal dendrites.
Proceedings of the National Academy of Sciences of the United States of America
Glanzer J,Miyashiro KY,Sul JY,Barrett L,Belt B,Haydon P,Eberwine J
Tue Nov 15 00:00:00 UTC 2005
Alteration of cellular RNA splicing and polyadenylation machineries during productive human cytomegalovirus infection.
The Journal of general virology
Adair R,Liebisch GW,Su Y,Colberg-Poley AM
32-4500 was used in western blot to study human cytomegalovirus UL37 isoforms
Wed Dec 01 00:00:00 UTC 2004
RNA folding affects the recruitment of SR proteins by mouse and human polypurinic enhancer elements in the fibronectin EDA exon.
Molecular and cellular biology
Buratti E,Muro AF,Giombi M,Gherbassi D,Iaconcig A,Baralle FE
Sun Feb 01 00:00:00 UTC 2004
RNA folding affects the recruitment of SR proteins by mouse and human polypurinic enhancer elements in the fibronectin EDA exon.
Molecular and cellular biology
Buratti E,Muro AF,Giombi M,Gherbassi D,Iaconcig A,Baralle FE
Sun Feb 01 00:00:00 UTC 2004
Roles for SR proteins and hnRNP A1 in the regulation of c-src exon N1.
Molecular and cellular biology
Rooke N,Markovtsov V,Cagavi E,Black DL
Sat Mar 01 00:00:00 UTC 2003
