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Application
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SRSF5 Antibody (PA5-60383) in ICC/IF
Immunofluorecent analysis of SRSF5 in human cell line U-2 OS using SRSF5 Polyclonal Antibody (Product # PA5-60383). Staining shows localization to nucleus and nucleoli.
Product Details
PA5-60383
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SRSF5. Recombinant protein control fragment (Product #RP-100370).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.30 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2647942
Product Specific Information
Immunogen sequence: KELCSERVTI EHARARSRGG RGRGRYSDRF SSRRPRNDRR NAPPVRTE
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
SR proteins are a highly conserved family of arginine/serine-rich, spliceosome-associated phosphoproteins essential for metazoan pre-mRNA splicing. SR proteins act early in splicing by promoting splice site recognition and spliceosome assembly. SR proteins also play a regulatory role because they can determine alternative splice site usage in vivo and in vitro. SR proteins appear to be recruited from nuclear 'speckles', in which they are concentrated to sites of transcription in order to spatially coordinate transcription and pre-mRNA splicing within the cell nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Delayed-early protein HRS; Insulin-induced growth response protein CL-4; Pre-mRNA-splicing factor SRP40; Serine/arginine-rich splicing factor 5; splicing factor arginine/serine-rich 5 (SRp40 HRS); Splicing factor, arginine/serine-rich 5; splicing factor, arginine/serine-rich 5 (SRp40, HRS); SR splicing factor 5
Gene Aliases: Cl-4; HRS; SFRS5; SRP40; SRSF5
UniProt ID: (Human) Q13243, (Rat) Q09167, (Mouse) O35326
Entrez Gene ID: (Human) 6430, (Rat) 29667, (Mouse) 20384
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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