Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
The antibody detects endogenous levels of total STAG3 protein.
STAG3 is a meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cohesin subunit SA-3; MGC119262; MGC119264; MGC119265; NHLRC 1; SCC3 homolog 3; Stromal antigen 3; Stromalin 3; Stromalin-3
Gene Aliases: STAG3
UniProt ID: (Human) Q9UJ98
Entrez Gene ID: (Human) 10734
Molecular Function:
chromatin/chromatin-binding, or -regulatory protein
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