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Antibody detects endogenous levels of total STA13.
This gene encodes a protein which contains an N-terminal sterile alpha motif (SAM) for protein-protein interactions, followed by an ATP/GTP-binding motif, a GTPase-activating protein (GAP) domain, and a C-terminal STAR-related lipid transfer (START) domain. It may be involved in regulation of cytoskeletal reorganization, cell proliferation, and cell motility, and acts as a tumor suppressor in hepatoma cells. The gene is located in a region of chromosome 13 that is associated with loss of heterozygosity in hepatocellular carcinomas. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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Protein Aliases: 46H23.2; Deleted in liver cancer 2 protein; DLC-2; long intergenic non-protein coding RNA 464; Rho GTPase activating protein on chromosome 13q12; Rho GTPase-activating protein; serologically defined colon cancer antigen 13; serologically defined colon cancer antigen 28; STA13; StAR-related lipid transfer (START) domain containing 13; StAR-related lipid transfer domain containing 13; StAR-related lipid transfer protein 13; StARD13; START domain-containing protein 13
Gene Aliases: ARHGAP37; DLC2; GT650; LINC00464; STARD13
UniProt ID: (Human) Q9Y3M8, (Mouse) Q923Q2
Entrez Gene ID: (Human) 90627, (Mouse) 243362
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