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Product Details
66719-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1H8E4
Immunogen
STK11 Fusion Protein Ag13436 (133-433 aa encoded by BC007981)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: VCGMQEMLD SVPEKRFPVC QAHGYFCQLI DGLEYLHSQG IVHKDIKPGN LLLTTGGTLK ISDLGVAEAL HPFAADDTCR TSQGSPAFQP PEIANGLDTF SGFKVDIWSA GVTLYNITTG LYPFEGDNIY KLFENIGKGS YAIPGDCGPP LSDLLKGMLE YEPAKRFSIR QIRQHSWFRK KHPPAEAPVP IPPSPDTKDR WRSMTVVPYL EDLHGADEDE DLFDIEDDII YTQDFTVPGQ VPEEEASHNG QRRGLPKAVC MNGTEAAQLS TKSRAEGRAP NPARKACSAS SKIRRLSACK QQ (133-433 aa encoded by BC007981)
Target Information
LKB1 (also known as STK11 - Serine/threonine-protein kinase STK11), a member of the serine/threonine kinase family, is a tumor suppressor. LKB1 physically associates with p53 and regulates specific p53 dependent apoptosis pathways. LKB1 is present in both the cytoplasm and nucleus of living cells and translocates to mitochondria during apoptosis. LKB1 functions as a master upstream protein kinase, regulating AMPK related kinases as well as AMPK. Mutations in LKB1 gene are associated with Peutz Jeghers syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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