Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
14923-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SUCLG1 Fusion Protein Ag6481 (1-333 aa encoded by BC000504)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.17 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MVSGSSGLA AARLLSRSFL LPQNGIRHCS YTASRQHLYV DKNTKIICQG FTGKQGTFHS QQALEYGTKL VGGTTPGKGG QTHLGLPVFN TVKEAKEQTG ATASVIYVPP PFAAAAINEA IEAEIPLVVC ITEGIPQQDM VRVKHKLLRQ EKTRLIGPNC PGVINPGECK IGIMPGHIHK KGRIGIVSRS GTLTYEAVHQ TTQVGLGQSL CVGIGGDPFN GTDFIDCLEI FLNDSATEGI ILIGEIGGNA EENAAEFLKQ HNSGPNSKPV VSFIAGLTAP PGRRMGHAGA IIAGGKGGAK EKISALQSAG VVVSMSPAQL GTTIYKEFEK RKML (1-333 aa encoded by BC000504)
Target Information
This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depletion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: SCS-alpha; Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; succinate-CoA ligase, alpha subunit; succinate-CoA ligase, GDP-forming alpha subunit; succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial; succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase subunit alpha
Gene Aliases: 1500000I01Rik; GALPHA; MTDPS9; SUCLA1; SUCLG1
UniProt ID: (Human) P53597, (Rat) P13086, (Mouse) Q9WUM5
Entrez Gene ID: (Human) 8802, (Rat) 114597, (Mouse) 56451
succinate-CoA ligase (ADP-forming) activity
succinate-CoA ligase (GDP-forming) activity
GTP binding
poly(A) RNA binding
cofactor binding
ATP citrate synthase activity
GDP binding
protein heterodimerization activity
nucleotide binding
catalytic activity
ligase activity
ligase
metabolite interconversion enzyme
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support