Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MPGLTCFTH DNQHWQTAPF WTLGPFCACT SANNNTYWCM RTINETHNFL FCEFATGFLE YFDLNTDPYQ LMNAVNTLDR DVLNQLHVQL MELRSCKGYK QCNPRTRNMD LGLKDGGSYE QYRQFQRRKW PEMKRPSSKS LGQLWEGWEG (722-870 aa encoded by BC020962)
Heparan sulfate 6-O-endosulfatases, such as Sulfatase 2, selectively remove 6-O-sulfate groups from heparan sulfate. Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 ).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Arylsulfatase; DKFZp313E091; Extracellular sulfatase Sulf-2; FLJ44488; FLJ90554; hSulf-2; MGC126411; mSulf-2; N-acetylglucosamine-6-sulfatase; OTTHUMP00000031223; RP5-1049G16.1; sulfatase FP2
Gene Aliases: 2010004N24Rik; AU020235; HSULF-2; KIAA1247; mKIAA1247; MSulf-2; SULF2; UNQ559/PRO1120
UniProt ID: (Human) Q8IWU5, (Mouse) Q8CFG0
Entrez Gene ID: (Human) 55959, (Rat) 311642, (Mouse) 72043
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