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            • Primary Antibodies ›
            • SULF2 Antibodies

            Invitrogen

            SULF2 Polyclonal Antibody

            View all (7) SULF2 antibodies
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            Cite SULF2 Polyclonal Antibody

            Product Details

            PA1-12860

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            0.05-0.1 µg/mL
            -
            Product Specifications

            Species Reactivity

            Human

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Synthetic peptide corresponding to human Sulf2.

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            1 mg/mL

            Purification

            Ammonium sulfate precipitation

            Storage buffer

            PBS

            Contains

            0.08% sodium azide

            Storage conditions

            -20°C, Avoid Freeze/Thaw Cycles

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_2197474

            Product Specific Information

            A suggested positive control for this product is human brain lysate.

            Target Information

            Heparan sulfate 6-O-endosulfatases, such as Sulfatase 2, selectively remove 6-O-sulfate groups from heparan sulfate. Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 ).

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: Arylsulfatase; DKFZp313E091; Extracellular sulfatase Sulf-2; FLJ44488; FLJ90554; hSulf-2; MGC126411; N-acetylglucosamine-6-sulfatase; OTTHUMP00000031223; RP5-1049G16.1

            View more View less

            Gene Aliases: HSULF-2; KIAA1247; SULF2; UNQ559/PRO1120

            View more View less

            UniProt ID: (Human) Q8IWU5

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            Entrez Gene ID: (Human) 55959

            View more View less

            Function(s)

            arylsulfatase activity calcium ion binding N-acetylglucosamine-6-sulfatase activity hydrolase

            Process(es)

            kidney development chondrocyte development glomerular filtration response to wounding positive regulation of vascular endothelial growth factor production esophagus smooth muscle contraction positive regulation of Wnt signaling pathway heparan sulfate proteoglycan metabolic process glomerular basement membrane development positive regulation of catenin import into nucleus glial cell-derived neurotrophic factor receptor signaling pathway negative regulation of fibroblast growth factor receptor signaling pathway embryonic skeletal system development cartilage development bone development innervation positive regulation of canonical Wnt signaling pathway liver regeneration regulation of hepatocyte proliferation
            It has to be done as per old AB suggested Products section.
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            Performance Guarantee

            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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