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SUMO2/SUMO3 Polyclonal Antibody

Tech Support

Datasheet

Protocols

Questions & Answers

Tech Support

Product Details

OSS00112G-500UG

Applications

Tested Dilution

Publications

Western Blot (WB)

10-50 µg/mL

Immunohistochemistry (IHC)

10-50 µg/mL

Miscellaneous PubMed (Misc)

View 3 publications 3 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Not Applicable

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide from the n-terminal of rat SUMO2 & SUMO3 (Small ubiquitin-related modifier 2 and 3) conjugated to an immunogenic carrier protein was used as the immunogen

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

Conc. Not Determined

Purification

Ammonium sulfate precipitation

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

The antigen is homologous in many species including human, mouse and chicken.

Specificity of this antibody: SUMO2 and SUMO3.

Target Information

This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

Nature

Zody MC,Garber M,Adams DJ,Sharpe T,Harrow J,Lupski JR,Nicholson C,Searle SM,Wilming L,Young SK,Abouelleil A,Allen NR,Bi W,Bloom T,Borowsky ML,Bugalter BE,Butler J,Chang JL,Chen CK,Cook A,Corum B,Cuomo CA,de Jong PJ,DeCaprio D,Dewar K,FitzGerald M,Gilbert J,Gibson R,Gnerre S,Goldstein S,Grafham DV,Grocock R,Hafez N,Hagopian DS,Hart E,Norman CH,Humphray S,Jaffe DB,Jones M,Kamal M,Khodiyar VK,LaButti K,Laird G,Lehoczky J,Liu X,Lokyitsang T,Loveland J,Lui A,Macdonald P,Major JE,Matthews L,Mauceli E,McCarroll SA,Mihalev AH,Mudge J,Nguyen C,Nicol R,O'Leary SB,Osoegawa K,Schwartz DC,Shaw-Smith C,Stankiewicz P,Steward C,Swarbreck D,Venkataraman V,Whittaker CA,Yang X,Zimmer AR,Bradley A,Hubbard T,Birren BW,Rogers J,Lander ES,Nusbaum C

Thu Apr 20 00:00:00 EDT 2006

The transcriptional landscape of the mammalian genome.

Science (New York, N.Y.)

Carninci P,Kasukawa T,Katayama S,Gough J,Frith MC,Maeda N,Oyama R,Ravasi T,Lenhard B,Wells C,Kodzius R,Shimokawa K,Bajic VB,Brenner SE,Batalov S,Forrest AR,Zavolan M,Davis MJ,Wilming LG,Aidinis V,Allen JE,Ambesi-Impiombato A,Apweiler R,Aturaliya RN,Bailey TL,Bansal M,Baxter L,Beisel KW,Bersano T,Bono H,Chalk AM,Chiu KP,Choudhary V,Christoffels A,Clutterbuck DR,Crowe ML,Dalla E,Dalrymple BP,de Bono B,Della Gatta G,di Bernardo D,Down T,Engstrom P,Fagiolini M,Faulkner G,Fletcher CF,Fukushima T,Furuno M,Futaki S,Gariboldi M,Georgii-Hemming P,Gingeras TR,Gojobori T,Green RE,Gustincich S,Harbers M,Hayashi Y,Hensch TK,Hirokawa N,Hill D,Huminiecki L,Iacono M,Ikeo K,Iwama A,Ishikawa T,Jakt M,Kanapin A,Katoh M,Kawasawa Y,Kelso J,Kitamura H,Kitano H,Kollias G,Krishnan SP,Kruger A,Kummerfeld SK,Kurochkin IV,Lareau LF,Lazarevic D,Lipovich L,Liu J,Liuni S,McWilliam S,Madan Babu M,Madera M,Marchionni L,Matsuda H,Matsuzawa S,Miki H,Mignone F,Miyake S,Morris K,Mottagui-Tabar S,Mulder N,Nakano N,Nakauchi H,Ng P,Nilsson R,Nishiguchi S,Nishikawa S,Nori F,Ohara O,Okazaki Y,Orlando V,Pang KC,Pavan WJ,Pavesi G,Pesole G,Petrovsky N,Piazza S,Reed J,Reid JF,Ring BZ,Ringwald M,Rost B,Ruan Y,Salzberg SL,Sandelin A,Schneider C,Schönbach C,Sekiguchi K,Semple CA,Seno S,Sessa L,Sheng Y,Shibata Y,Shimada H,Shimada K,Silva D,Sinclair B,Sperling S,Stupka E,Sugiura K,Sultana R,Takenaka Y,Taki K,Tammoja K,Tan SL,Tang S,Taylor MS,Tegner J,Teichmann SA,Ueda HR,van Nimwegen E,Verardo R,Wei CL,Yagi K,Yamanishi H,Zabarovsky E,Zhu S,Zimmer A,Hide W,Bult C,Grimmond SM,Teasdale RD,Liu ET,Brusic V,Quackenbush J,Wahlestedt C,Mattick JS,Hume DA,Kai C,Sasaki D,Tomaru Y,Fukuda S,Kanamori-Katayama M,Suzuki M,Aoki J,Arakawa T,Iida J,Imamura K,Itoh M,Kato T,Kawaji H,Kawagashira N,Kawashima T,Kojima M,Kondo S,Konno H,Nakano K,Ninomiya N,Nishio T,Okada M,Plessy C,Shibata K,Shiraki T,Suzuki S,Tagami M,Waki K,Watahiki A,Okamura-Oho Y,Suzuki H,Kawai J,Hayashizaki Y

Fri Sep 02 00:00:00 EDT 2005

Characterization of mouse ubiquitin-like SMT3A and SMT3B cDNAs and gene/pseudogenes.

Biochemistry and molecular biology international

Chen A,Mannen H,Li SS

Tue Dec 01 00:00:00 EST 1998

Bioinformatics

Protein Aliases: HSMT3; sentrin 2; Sentrin-2; Small ubiquitin-related modifier 2; Small ubiquitin-related modifier 3; SMT3 (supressor of mif two, 3) homolog 1; SMT3 homolog 1; SMT3 homolog 2; SMT3 suppressor of mif two 3 homolog 1; SMT3 suppressor of mif two 3 homolog 2; SMT3 suppressor of mif two 3 homolog 3; SMT3 supressor of mif two 3 homolog 2; Smt3A; Smt3B; SMT3C; SMT3H3; SUMO-2; SUMO-3; Ubiquitin-like protein SMT3A; Ubiquitin-like protein SMT3B; UBL1

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Gene Aliases: 2810014B19Rik; D10Ertd345e; HSMT3; SMT3A; SMT3B; SMT3H1; SMT3H2; SUMO-2; SUMO-3; SUMO2; SUMO3

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UniProt ID: (Human) P61956, (Human) P55854, (Rat) P61959, (Mouse) P61957, (Rat) Q5XIF4, (Mouse) Q9Z172

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Entrez Gene ID: (Human) 6613, (Human) 6612, (Rat) 690244, (Mouse) 170930, (Rat) 499417, (Mouse) 20610

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Function(s)

protein binding protein tag ubiquitin protein ligase binding poly(A) RNA binding SUMO transferase activity

Process(es)

protein sumoylation positive regulation of proteasomal ubiquitin-dependent protein catabolic process cellular protein localization negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter global genome nucleotide-excision repair protein localization to nucleus positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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SUMO2/SUMO3 Polyclonal Antibody

Product Details

OSS00112G-500UG

Western Blot (WB)

Immunohistochemistry (IHC)

Miscellaneous PubMed (Misc)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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