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Bioss
Serine/threonine-protein kinase MAK-V Polyclonal Antibody
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Product Details
BS-11990R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Serine/threonine-protein kinase MAK-V, amino acids 71-115.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
HUNK serine/threonine kinase or hormonally up-regulated Neu-associated kinase is a member of the mitogen-activated protein kinase family which is essential for mammary tumor metastasis. HUNK deletion in mice did not alter viability, fertility, longevity, or propensity to develop tumors and it is also dispensable for murine development. HUNK has been shown to participate in vesicular transport. Additionally, functional studies in mice suggest that HUNK regulates endocytosis via interaction with rabaptin-5 protein and induces changes in mammary glands during pregnancy. HUNK expression has been documented in mouse brain, breast, embryo, and fetus. ESTs have been isolated from several human tissue libraries, including normal ear.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B19; Hormonally up-regulated neu tumor-associated kinase; hormonally upregulated neu tumor-associated kinase; hormonally upregulated Neu-associated kinase; serine/threonine protein kinase MAK-V; Serine/threonine-protein kinase MAK-V
Gene Aliases: Bstk1; HUNK; Mak-v; MAKV; RGD1565091
UniProt ID: (Human) P57058, (Mouse) O88866
Entrez Gene ID: (Human) 30811, (Mouse) 26559, (Rat) 288275
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