Invitrogen antibodies—maximize lab budgets with advanced validation & coverage

Shop antibodies

Hamburger Menu Button
Thermo Fisher Scientific Logo
Sign in
Don't have an account ? Create Account
  • Productos
    • Anticuerpos
    • Oligonucleótidos, cebadores, sondas y genes
    • Ensayos de PCR en tiempo real TaqMan
    • Medios de cultivos celulares
    • Productos químicos
    • Columnas y cartuchos de cromatografía
    • Equipo de laboratorio
    • Material de plástico y suministros para laboratorio
    • Microplacas
    • Productos más ecológicos
    • Ver todas las categorías de productos
  • Applications
    • Bioprocesamiento
    • Cultivo celular y transfección
    • Terapia celular y génica
    • Cromatografía
    • Pruebas moleculares
    • Soluciones digitales
    • Extracción y análisis de ADN y ARN
    • Espectroscopía, análisis elemental y de isótopos
    • Ver todas las aplicaciones y técnicas
  • Servicios
    • Servicios 360° de CDMO y CRO
    • Servicios de CDMO
    • Servicios de CRO
    • Servicios personalizados
    • Servicios empresariales
    • Servicios de leasing y financiación
    • Servicios de instrumentos
    • Informática de laboratorio
    • OEM y oferta comercial
    • Servicios de formación
    • Unity Lab Services
    • Ver todos los servicios
  • Ayuda y soporte técnico
    • Regístrese para obtener una cuenta
    • Cómo hacer un pedido
    • Asistencia para el instrumental
    • Centros de soporte técnico
    • Centros de formación
    • Vea todos los temas de ayuda y soporte técnico
  • Popular
    • TaqMan Real-Time PCR Assays
      TaqMan Real-Time PCR Assays
    • Antibodies
      Antibodies
    • Oligos, Primers & Probes
      Oligos, Primers & Probes
    • GeneArt Gene Synthesis
      GeneArt Gene Synthesis
    • Cell Culture Plastics
      Cell Culture Plastics
  • Ofertas especiales
  • Contacto
  • Pedido rápido
  • Estado del pedido y seguimiento
  • Documentos y certificados
Thermo Fisher Scientific Logo

Search Thermo Fisher Scientific

Anticuerpos primarios
  • Buscar
  • Popular Product Areas
  • Ensayos TaqMan
  • Expresión génica
  • Anticuerpos primarios
  • Anticuerpos Secundarios
  • Controles de isotipo
  • Proteínas y péptidos
  • Kits ELISA
  • SNP Genotyping
  • Todos los documentos y soporte
  • Certificados
  • SDS
  • Preguntas frecuentes sobre productos
  • Manuales y Protocolos
    Search button Close
            • Estado del pedido
            • Pedido rápido
            • Sign in
              Sign in
              Don't have an account ? Create Account
              • Cuenta
              • Pedidos
              • Connect: laboratorio, datos, aplicaciones
              • Productos y proyectos personalizados
              • Services Central

            Disclaimer

            Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

            Loading ...
            • Primary Antibodies ›
            • Nhe-1 Antibodies

            Fabgennix

            Sodium/Hydrogen Exchanger 1 Polyclonal Antibody

            View all (17) Nhe-1 antibodies
            Datasheet
            Protocols
            Questions & Answers
            Tech Support
            Datasheet
            Protocols
            Questions & Answers
            Tech Support

            Cite Sodium/Hydrogen Exchanger 1 Polyclonal Antibody

            • Antibody Testing Data (1)
            Application
            Sodium/Hydrogen Exchanger 1 Antibody in Immunohistochemistry (IHC)
            Group 53 Created with Sketch.

            FIGURE: 1 / 1

            Sodium/Hydrogen Exchanger 1 Antibody (NHE1-101AP) in IHC

            Baboon Large Intestine- Sodium / Hydrogen Exchanger 1 Primary Antibody: NHE1-101AP; 1:50 dilution in IHC Blocking Buffer. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 40X magnification. FFPE section.
            View Product

            Sodium/Hydrogen Exchanger 1 Antibody in Immunohistochemistry (IHC)

            Product Details

            NHE1-101AP

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:500-1:1,000
            -

            Immunohistochemistry (IHC)

            1:50
            -

            ELISA (ELISA)

            1:10,000
            -

            Immunoprecipitation (IP)

            1:50-1:250
            -
            Product Specifications

            Species Reactivity

            Human, Mouse, Non-human primate, Rat

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Synthetic peptide taken within amino acid region 700-750 on human Sodium/hydrogen exchanger 1 / SLC9A1 protein.
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            0.5-1.5 mg/mL

            Purification

            Affinity chromatography

            Storage buffer

            proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA

            Contains

            0.02% sodium azide

            Storage conditions

            -20°C

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            Target Information

            The Na+/H+ antiporter (Nhe-1) is a ubiquitous membrane-bound enzyme involved in pH regulation of vertebrate cells and is specifically inhibited by the diuretic drug amiloride and activated by a variety of signals including growth factors, mitogens, neurotransmitters, and tumor promoters. Nhe-1 acts as an anchor for actin filaments to control the integrity of the cortical cytoskeleton. This occurs through a previously unrecognized structural link between Nhe-1 and the actin-binding proteins ezrin, radixin, and moesin, collectively referred to as ERM proteins. A structural role for Nhe-1 has been proposed in regulating the cortical cytoskeleton that is independent of its function as an ion exchanger. It is also thought that Nhe-1 play a role in hypertension. At least two isoforms of Nhe-1 are known to exist.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

            Have you cited this product in a publication?
            Let us know so we can reference it here.
            Cite this product

            Bioinformatics

            Protein Aliases: APNH; Na(+)/H(+) antiporter, amiloride-sensitive; Na(+)/H(+) exchanger 1; Na+/H+ antiporter; Na+/H+, amiloride sensitive; Na-Li countertransporter; NHE-1; protein phosphatase 1, regulatory subunit 143; slow-wave epilepsy; Sodium/hydrogen exchanger 1; Solute carrier family 9 (sodium/hydrogen exchanger 1), antiporter, Na+/H+, (amiloride sensitive); solute carrier family 9 (sodium/hydrogen exchanger), isoform 1 (antiporter, Na+/H+, amiloride sensitive); solute carrier family 9 (sodium/hydrogen exchanger), member 1; solute carrier family 9 (sodium/hydrogen exchanger), member 1 (antiporter, Na+/H+, amiloride sensitive); Solute carrier family 9 member 1; solute carrier family 9, member 1; solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1

            View more View less

            Gene Aliases: APNH; APNH1; AW554487; LIKNS; mir-5122; Mir5122; NHE-1; NHE1; PPP1R143; SLC9A1; swe

            View more View less

            UniProt ID: (Human) P19634, (Rat) P26431, (Mouse) Q61165

            View more View less

            Entrez Gene ID: (Human) 6548, (Rat) 24782, (Mouse) 20544

            View more View less

            Function(s)

            protein binding calmodulin binding phosphatidylinositol-4,5-bisphosphate binding solute:proton antiporter activity sodium:proton antiporter activity potassium:proton antiporter activity protein phosphatase 2B binding protein binding, bridging protein complex scaffold calcium-dependent protein binding sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential antiporter activity transporter secondary carrier transporter

            Process(es)

            ion transport cellular sodium ion homeostasis regulation of pH response to acidic pH positive regulation of cardiac muscle hypertrophy regulation of cardiac muscle contraction by calcium ion signaling cell growth cell migration maintenance of cell polarity hyaluronan catabolic process positive regulation of cell growth cellular response to insulin stimulus positive regulation of mitochondrial membrane permeability response to muscle stretch response to drug positive regulation of apoptotic process negative regulation of apoptotic process positive regulation of action potential positive regulation of transcription from RNA polymerase II promoter protein oligomerization regulation of intracellular pH regulation of stress fiber assembly positive regulation of NFAT protein import into nucleus regulation of focal adhesion assembly regulation of sensory perception of pain cardiac muscle cell differentiation positive regulation of calcineurin-NFAT signaling cascade neuron death cellular response to antibiotic cellular response to electrical stimulus cellular response to mechanical stimulus sodium ion export cellular response to hypoxia cellular response to acidic pH potassium ion transmembrane transport cellular response to epinephrine stimulus cardiac muscle cell contraction regulation of cardiac muscle cell membrane potential regulation of the force of heart contraction by cardiac conduction sodium ion import across plasma membrane positive regulation of the force of heart contraction hydrogen ion transmembrane transport positive regulation of calcium:sodium antiporter activity regulation of the force of heart contraction sodium ion transport response to organic cyclic compound cell differentiation sodium ion transmembrane transport cellular response to organic cyclic compound positive regulation of intracellular signal transduction transport cation transport embryo development transmembrane transport
            It has to be done as per old AB suggested Products section.
            guarantee_icon

            Performance Guarantee

            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

            Learn more
            help_icon

            We're here to help

            Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

            Contact tech support
            Pedidos Plus Icon Minus Icon
            • Estado del pedido
            • Ayuda con el pedido
            • Pedido rápido
            • Centro de suministros
            • eProcurement (B2B)
            Asistencia Plus Icon Minus Icon
            • Ayuda y soporte técnico
            • Contacto
            • Centros de soporte técnico
            • Documentos y certificados
            • Informar de un problema del sitio web
            Recursos Plus Icon Minus Icon
            • Centros de formación
            • Promociones
            • Eventos y seminarios web
            • Redes sociales
            Acerca de Thermo Fisher Plus Icon Minus Icon
            • Acerca de nosotros
            • Carreras profesionales
            • Inversores
            • Noticias
            • Responsabilidad social
            • Marcas registradas
            Nuestra cartera Plus Icon Minus Icon
            • Thermo Scientific
            • Applied Biosystems
            • Invitrogen
            • Gibco
            • Ion Torrent
            • Fisher Scientific
            • Unity Lab Services
            • Patheon
            • PPD
            • Terms & Conditions
            • Privacy Information Center
            • Price & Freight Policy
            • Preferencias sobre cookies

              Su elección con respecto a las cookies en este sitio

              Nosotros y nuestras empresas afiliadas y proveedores utilizamos cookies y tecnologías similares para gestionar nuestros sitios web, reconocer a los visitantes de nuestros sitios web, proporcionar un inicio de sesión seguro, recopilar estadísticas para optimizar las funciones del sitio web y ofrecer contenido adaptado a sus intereses. Haga clic en “Aceptar todas” para aceptar todas las cookies e ir directamente al sitio web; haga clic en “Rechazar todas” para rechazar todas las cookies excepto las estrictamente necesarias para el funcionamiento de este sitio web (cookies obligatorias) o haga clic en “Administrar configuraciones” para ver las descripciones detalladas de los tipos de cookies y elegir si acepta ciertas cookies mientras visita el sitio web.
            © 2006-2025 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.
            Spain flag icon
            Spain

            Your items have has been added!


            Host server : magellan-search-green-56756dfb8b-7vhdw:80/100.66.79.199:80.
            git-commit: de6905f249d25e22729e613aef254bb544bd8b7c
            git-url: https://github.com/thermofisher/magellan-search
            git-branch: release/2.31.1-2025.06.25-1.0