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Invitrogen
Spartalizumab Humanized Recombinant Human Monoclonal Antibody
Application
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Spartalizumab Humanized Antibody (MA5-58363) in ELISA
ELISA analysis of Spartalizumab Recombinant monoclonal antibody (Product # MA5-58363). Immobilized human PD-1 His at 2 µg/mL can bind (spartalizumab), EC50=0.01484 µg/mL.
Product Details
MA5-58363
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Human
/ IgG4SP
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Conjugate
Unconjugated
Form
Lyophilized
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
25mM histidine, pH 6.2, with 8% sucrose, 0.01% Tween 80
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
AB_3681383
Product Specific Information
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.
Target Information
Spartalizumab (PDR001) is a humanized IgG4 monoclonal antibody that targets PD-1 with sub-nanomolar affinity to block its interaction with PD-L1/PD-L2, thereby preventing PD-1 mediated inhibitory signals Transduction leads to the activation of T cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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