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            Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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            • Primary Antibodies ›
            • SOD1 Antibodies

            QED Bioscience

            Superoxide dismutase (SOD) Cu/Zn Polyclonal Antibody

            View all (75) SOD1 antibodies
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            Cite Superoxide dismutase (SOD) Cu/Zn Polyclonal Antibody

            • Antibody Testing Data (2)
            Application
            Superoxide dismutase (SOD) Cu/Zn Antibody in Immunohistochemistry (IHC)
            Group 53 Created with Sketch.

            FIGURE: 1 / 2

            Superoxide dismutase (SOD) Cu/Zn Antibody (13002-100UL) in IHC

            Immunohistochemistry analysis using Rabbit Anti-SOD1 Polyclonal Antibody (13002). Tissue: Placenta. Species: Human. Primary Antibody: Rabbit Anti-SOD1 Polyclonal Antibody (13002) at 1:100. Courtesy of: Courtesy of Joan Telfer, University of Glasgow.
            View Product

            Superoxide dismutase (SOD) Cu/Zn Antibody in Immunohistochemistry (IHC)
            Superoxide dismutase (SOD) Cu/Zn Antibody in Western Blot (WB)

            Product Details

            13002-100UL

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1-2 µg/mL
            -

            Immunohistochemistry (IHC)

            1-10 µg/mL
            -
            Product Specifications

            Species Reactivity

            Bovine, Dog, Hamster, Human, Mouse, Non-human primate, Sheep, Pig, Rabbit, Rat, Xenopus

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Human Cu/Zn SOD Accession no.: P00441, NP_000445.1

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            1 mg/mL

            Purification

            Protein A

            Storage buffer

            PBS, pH 7, with 50% glycerol

            Contains

            0.09% sodium azide

            Storage conditions

            -20°C, Avoid Freeze/Thaw Cycles

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            Target Information

            SOD1 (superoxide dismutase) binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: Amyotrophic lateral sclerosis 1 (ALS1); Cu(2+)-Zn2+ superoxide dismutase; Cu-Zn superoxide dismutase; Cu-Zn superoxide dismutase C-terminal fragment (150AA); Cu-Zn-superoxide dismutase; Cu/Zn SOD; Cu/Zn superoxide dismutase; CuZn superoxide dismutase; epididymis secretory protein Li 44; HGNC:11179; hSod1; indophenoloxidase A; Indophenoloxidase A (IPOA); SOD, soluble; superoxide dismutase; Superoxide dismutase 1; Superoxide Dismutase 1 (SOD1); superoxide dismutase 1 soluble; superoxide dismutase 1, soluble; superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)); superoxide dismutase 1, soluble S homeolog; Superoxide dismutase [Cu-Zn]; superoxide dismutase, cystolic

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            Gene Aliases: ALS; ALS1; B430204E11Rik; Cu/Zn-SOD; CuZnSOD; HEL-S-44; homodimer; hSod1; Ipo-1; Ipo1; IPOA; SOD; Sod-1; SOD1; sod1-a; sod1-b; SOD1L1; SODC; XELAEV_18014289mg; xsodb

            View more View less

            UniProt ID: (Pig) P04178, (Bovine) P00442, (Human) P00441, (Rabbit) P09212, (Dog) Q8WNN6, (Mouse) P08228, (Rat) P07632

            View more View less

            Entrez Gene ID: (Pig) 397036, (Bovine) 281495, (Human) 6647, (Rabbit) 100009313, (Dog) 403559, (Sheep) 100270717, (Mouse) 20655, (Rat) 24786, (Chinese hamster) 100765091, (Xenopus) 100381040

            View more View less

            Function(s)

            superoxide dismutase activity ubiquitin-protein transferase activity copper ion binding protein binding zinc ion binding protein phosphatase 2B binding protein homodimerization activity chaperone binding identical protein binding Rac GTPase binding antioxidant activity oxidoreductase activity enzyme binding metal ion binding oxidoreductase

            Process(es)

            activation of MAPK activity protein polyubiquitination response to superoxide ovarian follicle development regulation of cytokine production positive regulation of cytokine production retina homeostasis myeloid cell homeostasis glutathione metabolic process superoxide metabolic process cellular iron ion homeostasis spermatogenesis embryo implantation cell aging sensory perception of sound locomotory behavior regulation of blood pressure response to heat response to organic substance transmission of nerve impulse removal of superoxide radicals peripheral nervous system myelin maintenance regulation of multicellular organism growth response to drug response to hydrogen peroxide positive regulation of catalytic activity proteasome-mediated ubiquitin-dependent protein catabolic process negative regulation of neuron apoptotic process interspecies interaction between organisms response to ethanol negative regulation of cholesterol biosynthetic process regulation of protein kinase activity muscle cell cellular homeostasis response to axon injury hydrogen peroxide biosynthetic process positive regulation of nitric-oxide synthase biosynthetic process regulation of mitochondrial membrane potential oxidation-reduction process heart contraction neurofilament cytoskeleton organization relaxation of vascular smooth muscle auditory receptor cell stereocilium organization reactive oxygen species metabolic process response to reactive oxygen species placenta development response to amphetamine platelet degranulation anterograde axonal transport retrograde axonal transport response to nutrient levels positive regulation of superoxide anion generation regulation of T cell differentiation in thymus response to carbon monoxide cellular response to potassium ion superoxide anion generation positive regulation of apoptotic process regulation of GTPase activity regulation of organ growth response to antibiotic response to copper ion thymus development cellular response to cadmium ion cellular response to ATP response to antipsychotic drug positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway response to oxidative stress aging negative regulation of apoptotic process double-strand break repair apoptotic DNA fragmentation cellular response to oxidative stress
            It has to be done as per old AB suggested Products section.
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