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Application
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TACR2 Antibody (PA5-111739) in ICC/IF
Immunofluorecent analysis of TACR2 in human cell line A-431 using TACR2 Polyclonal Antibody (Product # PA5-111739). Staining shows localization to plasma membrane.
Product Details
PA5-111739
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human TACR2. Recombinant protein control fragment (Product #RP-108663).
Conjugate
Unconjugated
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2857149
Product Specific Information
Immunogen sequence: STVTMDQGAT KCVVAWPEDS GGKTLLL
Target Information
This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neuropeptide substance K, also referred to as neurokinin A.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: neurokinin 2 receptor; Neurokinin A receptor; NK-2 receptor; NK-2R; NK2; seven transmembrane helix receptor; SK receptor; SKR; substance K receptor; Substance-K receptor; Tachykinin receptor 2
Gene Aliases: NK2R; NKNAR; SKR; TAC2R; TACR2
UniProt ID: (Human) P21452
Entrez Gene ID: (Human) 6865
muscle contraction
cell surface receptor signaling pathway
tachykinin receptor signaling pathway
chemical synaptic transmission
excretion
positive regulation of acetylcholine secretion, neurotransmission
intestine smooth muscle contraction
negative regulation of luteinizing hormone secretion
operant conditioning
positive regulation of vascular permeability
positive regulation of smooth muscle contraction
response to electrical stimulus
prolactin secretion
positive regulation of uterine smooth muscle contraction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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