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Product Details
16124-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TARA Fusion Protein Ag9092 (5-379 aa encoded by BC013278)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.27 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: EATDSRTPE VPAGEGPRRG LGAPLTEDQQ NRLSEEIEKK WQELEKLPLR ENKRVPLTAL LNQSRGERRG PPSDGHEALE KEVQALRAQL EAWRLQGEAP QSALRSQEDG HIPPGYISQE ACERSLAEME SSHQQVMEEL QRHHERELQR LQQEKEWLLA EETAATASAI EAMKKAYQEE LSRELSKTRS LQQGPDGLRK QHQSDVEALK RELQVLSEQY SQKCLEIGAL MRQAEEREHT LRRCQQEGQE LLRHNQELHG RLSEEIDQLR GFIASQGMGN GCGRSNERSS CELEVLLRVK ENELQYLKKE VQCLRDELQM MQKDKRFTSG KYQDVYVELS HIKTRSEREI EQLKEHLRLA MAALQEKESM RNSLAE (5-379 aa encoded by B C013278)
Target Information
This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Protein Tara; tara-like protein; TRF1-associated protein of 68 kDa; TRIO and F-actin-binding protein; Trio-associated repeat on actin
Gene Aliases: DFNB28; dJ37E16.4; HRIHFB2122; KIAA1662; TAP68; TARA; TRIOBP
UniProt ID: (Human) Q9H2D6
Entrez Gene ID: (Human) 11078
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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