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            • Primary Antibodies ›
            • TBX15/TBX18 Antibodies

            Invitrogen

            TBX15/TBX18 Polyclonal Antibody

            View all (2) TBX15/TBX18 antibodies
            Datasheet
            Protocols
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            Datasheet
            Protocols
            Questions & Answers

            Cite TBX15/TBX18 Polyclonal Antibody

            • Antibody Testing Data (2)
            Application
            TBX15/TBX18 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Group 53 Created with Sketch.

            FIGURE: 1 / 2

            TBX15/TBX18 Antibody (PA5-103258) in IHC (P)

            Immunohistochemistry analysis of paraffin-embedded TBX15/TBX18 in rat brain tissue. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with TBX15/TBX18 polyclonal antibody (Product # PA5-103258) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
            View Product

            TBX15/TBX18 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            TBX15/TBX18 Antibody in Western Blot (WB)

            Product Details

            PA5-103258

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:1,000-1:3,000
            -

            Immunohistochemistry (Paraffin) (IHC (P))

            1:50-1:200
            -

            Immunocytochemistry (ICC/IF)

            1:100-1:500
            -
            Product Specifications

            Species Reactivity

            Human, Mouse, Rat

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            A synthesized peptide derived from human TBX18(Accession O95935), corresponding to amino acid residues P170-P220.
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            1 mg/mL

            Purification

            Affinity chromatography

            Storage buffer

            PBS, pH 7.4, with 50% glycerol

            Contains

            0.02% sodium azide

            Storage conditions

            -20°C

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_2852620

            Product Specific Information

            Antibody detects endogenous levels of total TBX15/18.

            Target Information

            T-box transcription factors are a group of phylogenetically conserved genes that contain a uniquely defining DNA-binding domain, the T-box domain. These genes are believed to be involved in the regulation of development processes. In mouse embryo development, Tbx15 is expressed at the beginning of day 9.5, primarily in the craniofacial region and in the developing limbs. Twelve human T-box genes have been isolated so far. TBX 18 has been reported to be involved in numerous development processes and to act as an antiapoptotic factor.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: droopy ear; MmTBx8; T-box 14; T-box protein 14; T-box protein 15; T-box protein 18; T-box transcription factor TBX14; T-box transcription factor TBX15; T-box transcription factor TBX18

            View more View less

            Gene Aliases: 2810012F10Rik; 2810404D13Rik; CAKUT2; de; TBX14; TBX15; TBX18; Tbx8

            View more View less

            UniProt ID: (Human) Q96SF7, (Human) O95935, (Mouse) O70306, (Mouse) Q9EPZ6

            View more View less

            Entrez Gene ID: (Human) 6913, (Human) 9096, (Mouse) 21384, (Rat) 295315, (Rat) 315870, (Mouse) 76365

            View more View less

            Function(s)

            RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II transcription corepressor activity protein binding protein homodimerization activity protein heterodimerization activity transcription regulatory region sequence-specific DNA binding transcription factor activity, sequence-specific DNA binding DNA binding RNA polymerase II transcription factor binding molecular_function Rel homology transcription factor

            Process(es)

            negative regulation of transcription from RNA polymerase II promoter transcription, DNA-templated embryonic cranial skeleton morphogenesis negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation renal system development regulation of transcription, DNA-templated transcription from RNA polymerase II promoter embryonic skeletal system morphogenesis somitogenesis positive regulation of mesenchymal cell proliferation sinoatrial node development sensory perception of sound biological_process anterior/posterior axis specification morphogenesis of embryonic epithelium positive regulation of cell-cell adhesion cell differentiation anatomical structure formation involved in morphogenesis positive regulation of epithelial cell proliferation smooth muscle cell differentiation ureter development cochlea morphogenesis positive regulation of mesenchymal cell proliferation involved in ureter development multicellular organism development
            It has to be done as per old AB suggested Products section.
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            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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