Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MLPCFQLLRI GGGRGGDLYT FHPPAGAGCT YRLGHRADLC DVALRPQQEP GLISGIHAEL HAEPRGDDWR VSLEDHSSQG TLVNNVRLPR GHRLELSDGD LLTFGPEGPP GTSPSEFYFM FQQVRVKPQD FAAITIPRSR GEARVGAGFR PMLPSQGAPQ RPLSTFSPAP KATLILNSIG SLSKLRPQPL TFSPSWGGPK SLPVPAPPGE VGTTPSAPPQ RNRRKSVHRV LAELDDESEP PENPPPVLME PRKKLRVDKA PLTPTGNRRG RPRKYPVSAP MAPPAVGGGE PCAAPCCCLP QEETVAWVQC DGCDVWFHVA CVGCSIQAAR EADFRCPGCR AGIQT
TCF-19 (transcription factor 19), also known as SC1 or SC1-1, is a 345 amino acid protein that contains one FHA domain, a proline-rich domain and one PHD-type zinc finger. Localizing to the nucleus, TCF-19 is a growth regulated protein that is believed to function as a trans-activating factor with a role in the transcription of genes involved in the late stages of cell cycle progression (G1 to S transition or entry of cells into G2 and mitosis). TCF-19 is expressed preferentially in the G1-S phase of the cell cycle. The gene encoding TCF-19 localizes to a critical region on chromosome 6 that has been associated with psoriasis vulgaris, a disorder of the skin that is characterized by hyperproliferation of epidermal cells. This suggests that TCF-19, via its regulation of late cell cycle-specific genes, may play a role in the development of this disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DAMA-213L4.5; SC 1; SC1(TCF19)-6; SC1(TCF19)-7; SC1-1; SCI(TCF19)-4; TCF 19; TCF-19; Transcription factor 19; Transcription factor SC1
Gene Aliases: SC1; TCF-19; TCF19
UniProt ID: (Human) Q9Y242
Entrez Gene ID: (Human) 6941
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