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FIGURE: 1 / 2
TCP-1 epsilon Antibody (MA5-27824) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of TCP-1-epsilon was performed in HeLa cells fixed in ice-cold MeOH for 5 min. Green: TCP-1 epsilon Monoclonal Antibody (GT639) (Product # MA5-27824) diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 µm.
Product Details
MA5-27824
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Hamster,
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
GT639
Immunogen
Recombinant protein encompassing a sequence within the center region of human TCP1 epsilon. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2735388
Product Specific Information
Positive Control: 293T, A431, HeLa, HepG2
Predicted Reactivity: Mouse (94%), Rat (94%), Zebrafish (83%), Xenopus laevis (86%), Pig (96%), Chicken (88%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (95%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CCT-epsilon; Chaperonin containing T-complex polypeptide 1 subunit 5; chaperonin containing TCP1, subunit 5 (epsilon); epididymis secretory protein Li 69; T-complex protein 1 subunit epsilon; TCP-1-epsilon
Gene Aliases: CCT-epsilon; CCT5; CCTE; HEL-S-69; KIAA0098; PNAS-102; TCP-1-epsilon
UniProt ID: (Human) P48643
Entrez Gene ID: (Human) 22948, (Chinese hamster) 100757108
protein folding
binding of sperm to zona pellucida
response to virus
positive regulation of telomere maintenance via telomerase
protein stabilization
toxin transport
positive regulation of establishment of protein localization to telomere
positive regulation of protein localization to Cajal body
positive regulation of telomerase RNA localization to Cajal body
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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