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Immunogen sequence: ELKAEKDNAE IRVHTVEDYQ AIVDAEWNIL YDKLEKIHHS GAKVVLSKLP IGDVATQYFA DRDMFCAGRV PEEDLKRTMM ACGGSIQTSV NALSADVLGR CQVFEETQIG GERYNFFTGC PKAKTCTFIL RGGAEQFMEE TE
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.
The TCP1 eta gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CCT-eta; Chaperonin containing T-complex polypeptide 1 subunit 7; chaperonin containing t-complex polypeptide 1, eta subunit; chaperonin containing t-complex subunit eta; chaperonin subunit 7 (eta); HIV-1 Nef interacting protein; HIV-1 Nef-interacting protein; MGC110985; T-complex protein 1 subunit eta; TCP-1-eta
Gene Aliases: AA408524; AL022769; CCT7; CCTETA; CCTH; Cctz; NIP7-1; TCP1ETA
UniProt ID: (Human) Q99832, (Mouse) P80313
Entrez Gene ID: (Human) 10574, (Mouse) 12468, (Rat) 297406
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