Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: ASIREKAGHWF ATTTPIIGKG IMFAIKEGRV TTGVSSIASE DSRKVASVLN NAYYLDKMHY SIEGKDTHYF VKIGSADGDL VTLGTTIG
Highest antigen sequence identity to the following orthologs - mouse 99%, rat 99%.
Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Promotes the formation of filopodia and enlarged growth cone in neuronal cells. Induces homophilic cell-cell adhesion. May function as a cellular signal transducer. Isoform 2: Acts as a ligand of the ADGRL1 receptor. Mediates axon guidance and heterophilic cell-cell adhesion. {ECO:0000269 PubMed:21724987}. Ten-2 intracellular domain: Induces gene transcription inhibition. {ECO:0000250}.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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