Product References
MCL-1 Inhibitor S63845 Distinctively Affects Intramedullary and Extramedullary Hematopoiesis.
Pharmaceutics
Zhang H,Li F,Yang M,Zhang W,He M,Xu H,Wang C,Zhang Y,Wang W,Gao Y,Du X,Li Y
25-5921-82 was used in Flow cytometry/Cell sorting to demonstrate the effects of myeloid cell leukemia 1 (MCL-1) inhibitor on the intramedullary and extramedullary hematopoietic lineages, which is important for the selection of combinations of antitumor drugs and the prevention of adverse hematopoiesis-related effects.
Tue Mar 28 00:00:00 UTC 2023
OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage.
Nature
Wu XS,He XY,Ipsaro JJ,Huang YH,Preall JB,Ng D,Shue YT,Sage J,Egeblad M,Joshua-Tor L,Vakoc CR
25-5921-82 was used in Flow cytometry/Cell sorting to reveal that the POU2F3-OCA-T complex is the master regulator of tuft cell identity and a molecular vulnerability of tuft-cell-like small-cell lung cancer.
Fri Jul 01 00:00:00 UTC 2022
Hematopoietic-Mesenchymal Signals Regulate the Properties of Mesenchymal Stem Cells.
International journal of molecular sciences
Kanazawa S,Okada H,Riu D,Mabuchi Y,Akazawa C,Iwata J,Hoshi K,Hikita A
25-5921-82 was used in Flow cytometry/Cell sorting to suggest that a hematopoietic-mesenchymal signal exists, and that the state of the HSCs is important for the stability of MSC properties.
Tue Jul 26 00:00:00 UTC 2022
Engineered red blood cells carrying PCSK9 inhibitors persistently lower LDL and prevent obesity.
PloS one
Deshycka R,Sudaryo V,Huang NJ,Xie Y,Smeding LY,Choi MK,Ploegh HL,Lodish HF,Pishesha N
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Fri Dec 24 00:00:00 UTC 2021
GRHL3 activates FSCN1 to relax cell-cell adhesions between migrating keratinocytes during wound reepithelialization.
JCI insight
Kashgari G,Venkatesh S,Refuerzo S,Pham B,Bayat A,Klein RH,Ramos R,Ta AP,Plikus MV,Wang PH,Andersen B
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Wed Sep 08 00:00:00 UTC 2021
The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism.
eLife
Roy A,Tomaz da Silva M,Bhat R,Bohnert KR,Iwawaki T,Kumar A
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Tue Nov 23 00:00:00 UTC 2021
SnRNA sequencing defines signaling by RBC-derived extracellular vesicles in the murine heart.
Life science alliance
Valkov N,Das A,Tucker NR,Li G,Salvador AM,Chaffin MD,Pereira De Oliveira Junior G,Kur I,Gokulnath P,Ziegler O,Yeri A,Lu S,Khamesra A,Xiao C,Rodosthenous R,Srinivasan S,Toxavidis V,Tigges J,Laurent LC,Momma S,Kitchen R,Ellinor P,Ghiran I,Das S
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Wed Dec 01 00:00:00 UTC 2021
Hypoxia-sensing CAR T cells provide safety and efficacy in treating solid tumors.
Cell reports. Medicine
Kosti P,Opzoomer JW,Larios-Martinez KI,Henley-Smith R,Scudamore CL,Okesola M,Taher MYM,Davies DM,Muliaditan T,Larcombe-Young D,Woodman N,Gillett CE,Thavaraj S,Maher J,Arnold JN
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Tue Apr 20 00:00:00 UTC 2021
Myeloid cell subsets that express latency-associated peptide promote cancer growth by modulating T cells.
iScience
Gabriely G,Ma D,Siddiqui S,Sun L,Skillin NP,Abou-El-Hassan H,Moreira TG,Donnelly D,da Cunha AP,Fujiwara M,Walton LR,Patel A,Krishnan R,Levine SS,Healy BC,Rezende RM,Murugaiyan G,Weiner HL
25-5921-82 was used in Flow cytometry/Cell sorting to identify a previously unknown function by which LAPHi MCs promote tumor growth and offer therapeutic intervention to target these cells in cancer.
Fri Nov 19 00:00:00 UTC 2021
Mitochondrial Potentiation Ameliorates Age-Related Heterogeneity in Hematopoietic Stem Cell Function.
Cell stem cell
Mansell E,Sigurdsson V,Deltcheva E,Brown J,James C,Miharada K,Soneji S,Larsson J,Enver T
25-5921 was used in Flow cytometry/Cell sorting to demonstrate that MMP is a source of heterogeneity in old HSCs, and its pharmacological manipulation can alter transcriptional programs with beneficial consequences for function.
Thu Feb 04 00:00:00 UTC 2021
Sex Matters: Physiological Abundance of Immuno-Regulatory CD71+ Erythroid Cells Impair Immunity in Females.
Frontiers in immunology
Mashhouri S,Koleva P,Huynh M,Okoye I,Shahbaz S,Elahi S
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Mon Dec 20 00:00:00 UTC 2021
Inhibition of TGFβ improves hematopoietic stem cell niche and ameliorates cancer-related anemia.
Stem cell research & therapy
Wang B,Wang Y,Chen H,Yao S,Lai X,Qiu Y,Cai J,Huang Y,Wei X,Guan Y,Wang T,Wang J,Xiang AP
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Mon Jan 18 00:00:00 UTC 2021
Lef1 restricts ectopic crypt formation and tumor cell growth in intestinal adenomas.
Science advances
Heino S,Fang S,Lähde M,Högström J,Nassiri S,Campbell A,Flanagan D,Raven A,Hodder M,Nasreddin N,Xue HH,Delorenzi M,Leedham S,Petrova TV,Sansom O,Alitalo K
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Fri Nov 19 00:00:00 UTC 2021
Hlf Expression Marks Early Emergence of Hematopoietic Stem Cell Precursors With Adult Repopulating Potential and Fate.
Frontiers in cell and developmental biology
Tang W,He J,Huang T,Bai Z,Wang C,Wang H,Yang R,Ni Y,Hou J,Wang J,Zhou J,Yao Y,Gong Y,Hou S,Liu B,Lan Y
25-5921-82 was used in Flow cytometry/Cell sorting to develop an Hlf-tdTomato reporter mouse model and detected Hlf-tdTomato expression exclusively in the hematopoietic cells including part of the immunophenotypic CD45- and CD45+ pre-HSCs in the embryonic day (E) 10.5 AGM region.
Fri Oct 01 00:00:00 UTC 2021
C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor.
Cancer cell
Di Genua C,Valletta S,Buono M,Stoilova B,Sweeney C,Rodriguez-Meira A,Grover A,Drissen R,Meng Y,Beveridge R,Aboukhalil Z,Karamitros D,Belderbos ME,Bystrykh L,Thongjuea S,Vyas P,Nerlov C
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Mon May 11 00:00:00 UTC 2020
Nucleoside-modified mRNA vaccination partially overcomes maternal antibody inhibition of de novo immune responses in mice.
Science translational medicine
Willis E,Pardi N,Parkhouse K,Mui BL,Tam YK,Weissman D,Hensley SE
25-5921-82 was used in Flow Cytometry to demonstrate that influenza virus-specific maternal antibodies inhibited de novo antibody responses in mouse pups elicited by influenza virus infection or administration of conventional influenza vaccines.
Wed Jan 08 00:00:00 UTC 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Mon Mar 02 00:00:00 UTC 2020
Site-1 protease ablation in the osterix-lineage in mice results in bone marrow neutrophilia and hematopoietic stem cell alterations.
Biology open
Patra D,Kim J,Zhang Q,Tycksen E,Sandell LJ
25-5921 was used in Flow cytometry/Cell sorting to show that S1P has a role in the lineage specification of hematopoietic stem cells and/or their progenitors for development of a normal hematopoietic niche.
Tue Jun 23 00:00:00 UTC 2020
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Thu Sep 17 00:00:00 UTC 2020
Methylation of a CGATA element inhibits binding and regulation by GATA-1.
Nature communications
Yang L,Chen Z,Stout ES,Delerue F,Ittner LM,Wilkins MR,Quinlan KGR,Crossley M
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Fri May 22 00:00:00 UTC 2020
A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation.
Nature communications
Kim JM,Yang YS,Park KH,Ge X,Xu R,Li N,Song M,Chun H,Bok S,Charles JF,Filhol-Cochet O,Boldyreff B,Dinter T,Yu PB,Kon N,Gu W,Takarada T,Greenblatt MB,Shim JH
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Fri May 08 00:00:00 UTC 2020
G protein-coupled receptor 68 increases the number of B lymphocytes.
American journal of blood research
He X,Feng S,Hawkins C,Lawley L,Fan W,Xu Y,Zha XM,Fang J
25-5921 was used in Flow cytometry/Cell sorting to indicate that Gpr68 expression is upregulated in hematopoietic cells upon aging and during hematopoietic regeneration that ends up with increased number of B lymphocytes.
Mon Sep 28 00:00:00 UTC 2020
TNFAIP3 Plays a Role in Aging of the Hematopoietic System.
Frontiers in immunology
Smith MA,Culver-Cochran AE,Adelman ER,Rhyasen GW,Ma A,Figueroa ME,Starczynowski DT
25-5921-82 was used in Flow Cytometry to find that the expression of A20 is significantly reduced in aged hematopoietic stem and progenitor cells (HSPC) as compared to young HSPC.
Wed Apr 28 00:00:00 UTC 2021
Resolving Cell Cycle Speed in One Snapshot with a Live-Cell Fluorescent Reporter.
Cell reports
Eastman AE,Chen X,Hu X,Hartman AA,Pearlman Morales AM,Yang C,Lu J,Kueh HY,Guo S
25-5921 was used in Flow cytometry/Cell sorting to describe a genetically encoded fluorescent reporter that captures live-cell cycle speed using a single measurement.
Tue Jun 23 00:00:00 UTC 2020
Characterization of the pathoimmunology of necrotizing enterocolitis reveals novel therapeutic opportunities.
Nature communications
Cho SX,Rudloff I,Lao JC,Pang MA,Goldberg R,Bui CB,McLean CA,Stock M,Klassert TE,Slevogt H,Mangan NE,Cheng W,Fischer D,Gfroerer S,Sandhu MK,Ngo D,Bujotzek A,Lariviere L,Schumacher F,Tiefenthaler G,Beker F,Collins C,Kamlin COF,König K,Malhotra A,Tan K,Theda C,Veldman A,Ellisdon AM,Whisstock JC,Berger PJ,Nold-Petry CA,Nold MF
25-5921 was used in Flow cytometry/Cell sorting to implicate type 3 cytokines, TLRs and IL-37 as potential targets for novel Necrotizing enterocolitis therapies.
Fri Nov 13 00:00:00 UTC 2020
Elucidating the fundamental fibrotic processes driving abdominal adhesion formation.
Nature communications
Foster DS,Marshall CD,Gulati GS,Chinta MS,Nguyen A,Salhotra A,Jones RE,Burcham A,Lerbs T,Cui L,King ME,Titan AL,Ransom RC,Manjunath A,Hu MS,Blackshear CP,Mascharak S,Moore AL,Norton JA,Kin CJ,Shelton AA,Januszyk M,Gurtner GC,Wernig G,Longaker MT
25-5921 was used in Flow cytometry/Cell sorting to present a systematic analysis of mouse and human adhesion tissues.
Thu Aug 13 00:00:00 UTC 2020
Polychromic Reporter Mice Reveal Unappreciated Innate Lymphoid Cell Progenitor Heterogeneity and Elusive ILC3 Progenitors in Bone Marrow.
Immunity
Walker JA,Clark PA,Crisp A,Barlow JL,Szeto A,Ferreira ACF,Rana BMJ,Jolin HE,Rodriguez-Rodriguez N,Sivasubramaniam M,Pannell R,Cruickshank J,Daly M,Haim-Vilmovsky L,Teichmann SA,McKenzie ANJ
25-5921 was used in Flow cytometry/Cell sorting to identify a discrete ILC2-committed population and delineated transition states between early progenitors and a highly heterogeneous ILC1, ILC3, and NK precursor cell cluster.
Tue Jul 16 00:00:00 UTC 2019
miR-181a/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity.
PLoS biology
Łyszkiewicz M,Winter SJ,Witzlau K,Föhse L,Brownlie R,Puchałka J,Verheyden NA,Kunze-Schumacher H,Imelmann E,Blume J,Raha S,Sekiya T,Yoshimura A,Frueh JT,Ullrich E,Huehn J,Weiss S,Gutierrez MG,Prinz I,Zamoyska R,Ziętara N,Krueger A
25-5921-82 was used in Flow Cytometry to propose that intrathymic miR-181a/b-1 controls development of Treg cells and imposes a developmental legacy on their peripheral function.
Fri Mar 01 00:00:00 UTC 2019
Macrophages fine tune satellite cell fate in dystrophic skeletal muscle of mdx mice.
PLoS genetics
Madaro L,Torcinaro A,De Bardi M,Contino FF,Pelizzola M,Diaferia GR,Imeneo G,Bouchè M,Puri PL,De Santa F
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Tue Oct 01 00:00:00 UTC 2019
Omega-3 Fatty Acids Activate Ciliary FFAR4 to Control Adipogenesis.
Cell
Hilgendorf KI,Johnson CT,Mezger A,Rice SL,Norris AM,Demeter J,Greenleaf WJ,Reiter JF,Kopinke D,Jackson PK
25-5921-82 was used in Flow Cytometry to investigate whether preadipocytes use their cilia to sense and respond to external cues to remodel white adipose tissue.
Wed Nov 27 00:00:00 UTC 2019
PDGFRα+ stromal adipocyte progenitors transition into epithelial cells during lobulo-alveologenesis in the murine mammary gland.
Nature communications
Joshi PA,Waterhouse PD,Kasaian K,Fang H,Gulyaeva O,Sul HS,Boutros PC,Khokha R
25-5921 was used in Flow cytometry/Cell sorting to identify the transition of a PDGFRα+ mesenchymal cell population into mammary epithelial progenitors in mice.
Mon Apr 15 00:00:00 UTC 2019
Interleukin-15 Complex Treatment Protects Mice from Cerebral Malaria by Inducing Interleukin-10-Producing Natural Killer Cells.
Immunity
Burrack KS,Huggins MA,Taras E,Dougherty P,Henzler CM,Yang R,Alter S,Jeng EK,Wong HC,Felices M,Cichocki F,Miller JS,Hart GT,Johnson AJ,Jameson SC,Hamilton SE
25-5921-82 was used in Flow Cytometry to identify a regulatory role for cytokine-stimulated NK cells in the prevention of a pathogenic immune response.
Tue Apr 17 00:00:00 UTC 2018
A dual genetic tracing system identifies diverse and dynamic origins of cardiac valve mesenchyme.
Development (Cambridge, England)
Liu K,Yu W,Tang M,Tang J,Liu X,Liu Q,Li Y,He L,Zhang L,Evans SM,Tian X,Lui KO,Zhou B
25-5921 was used in Flow cytometry to provide a proof-of-principle application of the Nigri-nox system for in vivo mouse genomic engineering.
Mon Sep 17 00:00:00 UTC 2018
MyD88 is required for satellite cell-mediated myofiber regeneration in dystrophin-deficient mdx mice.
Human molecular genetics
Gallot YS,Straughn AR,Bohnert KR,Xiong G,Hindi SM,Kumar A
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Mon Oct 01 00:00:00 UTC 2018
Site-1 protease regulates skeletal stem cell population and osteogenic differentiation in mice.
Biology open
Patra D,DeLassus E,Mueller J,Abou-Ezzi G,Sandell LJ
25-5921 was used in Flow cytometry/Cell sorting to investigate the mechanistic contribution of Site-1 protease to bone development in mice.
Thu Feb 22 00:00:00 UTC 2018
Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow.
Nature communications
Xu C,Gao X,Wei Q,Nakahara F,Zimmerman SE,Mar J,Frenette PS
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Fri Jun 22 00:00:00 UTC 2018
Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias.
Nature communications
Chaudhury S,O'Connor C,Cañete A,Bittencourt-Silvestre J,Sarrou E,Prendergast Á,Choi J,Johnston P,Wells CA,Gibson B,Keeshan K
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Tue Dec 11 00:00:00 UTC 2018
A cryptic cycle in haematopoietic niches promotes initiation of malaria transmission and evasion of chemotherapy.
Nature communications
Lee RS,Waters AP,Brewer JM
25-5921 was used in Flow cytometry/Cell sorting to enumerate Plasmodium infected erythropoietic precursor cells using an in vivo rodent model of Plasmodium berghei.
Fri Apr 27 00:00:00 UTC 2018
Inducible developmental reprogramming redefines commitment to sexual development in the malaria parasite Plasmodium berghei.
Nature microbiology
Kent RS,Modrzynska KK,Cameron R,Philip N,Billker O,Waters AP
25-5921-82 was used in Flow cytometry/Cell sorting to show that in a rodent malaria parasite, Plasmodium berghei, conditional overexpression of AP2-G can be used to synchronously convert the great majority of the population into fertile gametocytes.
Thu Nov 01 00:00:00 UTC 2018
Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer.
Nature
Lim JS,Ibaseta A,Fischer MM,Cancilla B,O'Young G,Cristea S,Luca VC,Yang D,Jahchan NS,Hamard C,Antoine M,Wislez M,Kong C,Cain J,Liu YW,Kapoun AM,Garcia KC,Hoey T,Murriel CL,Sage J
25-5921 was used in Flow cytometry/Cell sorting to show that Notch signalling can be both tumour suppressive and pro-tumorigenic in small-cell lung cancer.
Thu May 18 00:00:00 UTC 2017
Vitamin A-Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancy.
Cell
Cabezas-Wallscheid N,Buettner F,Sommerkamp P,Klimmeck D,Ladel L,Thalheimer FB,Pastor-Flores D,Roma LP,Renders S,Zeisberger P,Przybylla A,Schönberger K,Scognamiglio R,Altamura S,Florian CM,Fawaz M,Vonficht D,Tesio M,Collier P,Pavlinic D,Geiger H,Schroeder T,Benes V,Dick TP,Rieger MA,Stegle O,Trumpp A
25-5921 was used in Flow cytometry/Cell sorting to highlight the impact of dietary vitamin A on the regulation of cell-cycle-mediated stem cell plasticity.
Thu May 18 00:00:00 UTC 2017
Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia.
Nature immunology
Fang J,Bolanos LC,Choi K,Liu X,Christie S,Akunuru S,Kumar R,Wang D,Chen X,Greis KD,Stoilov P,Filippi MD,Maciejewski JP,Garcia-Manero G,Weirauch MT,Salomonis N,Geiger H,Zheng Y,Starczynowski DT
25-5921 was used in Flow cytometry/Cell sorting to examine the significance of ubiquitin signalling in coordinating RNA processing by Toll-like receptor pathways during an immune response and in premalignant haematologic diseases.
Wed Feb 01 00:00:00 UTC 2017
Differential cytokine contributions of perivascular haematopoietic stem cell niches.
Nature cell biology
Asada N,Kunisaki Y,Pierce H,Wang Z,Fernandez NF,Birbrair A,Ma'ayan A,Frenette PS
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Wed Mar 01 00:00:00 UTC 2017
GATA4-dependent organ-specific endothelial differentiation controls liver development and embryonic hematopoiesis.
The Journal of clinical investigation
Géraud C,Koch PS,Zierow J,Klapproth K,Busch K,Olsavszky V,Leibing T,Demory A,Ulbrich F,Diett M,Singh S,Sticht C,Breitkopf-Heinlein K,Richter K,Karppinen SM,Pihlajaniemi T,Arnold B,Rodewald HR,Augustin HG,Schledzewski K,Goerdt S
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Wed Mar 01 00:00:00 UTC 2017
Intron 1 GATA site enhances ALAS2 expression indispensably during erythroid differentiation.
Nucleic acids research
Zhang Y,Zhang J,An W,Wan Y,Ma S,Yin J,Li X,Gao J,Yuan W,Guo Y,Engel JD,Shi L,Cheng T,Zhu X
25592182 was used in flow cytometry to characterize a int-1-GATA knockout mouse
Wed Jan 25 00:00:00 UTC 2017
GATA Factor-Regulated Samd14 Enhancer Confers Red Blood Cell Regeneration and Survival in Severe Anemia.
Developmental cell
Hewitt KJ,Katsumura KR,Matson DR,Devadas P,Tanimura N,Hebert AS,Coon JJ,Kim JS,Dewey CN,Keles S,Hao S,Paulson RF,Bresnick EH
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Mon Aug 07 00:00:00 UTC 2017
Engineered erythrocytes covalently linked to antigenic peptides can protect against autoimmune disease.
Proceedings of the National Academy of Sciences of the United States of America
Pishesha N,Bilate AM,Wibowo MC,Huang NJ,Li Z,Deshycka R,Bousbaine D,Li H,Patterson HC,Dougan SK,Maruyama T,Lodish HF,Ploegh HL
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Tue Mar 21 00:00:00 UTC 2017
Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity.
Breast cancer research : BCR
Chamberlin T,D'Amato JV,Arendt LM
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Wed Nov 29 00:00:00 UTC 2017
Gli1 identifies osteogenic progenitors for bone formation and fracture repair.
Nature communications
Shi Y,He G,Lee WC,McKenzie JA,Silva MJ,Long F
25-5921 was used in Flow cytometry/Cell sorting to study how Gli1 marks mesenchymal progenitors responsible for both normal bone formation and fracture repair.
Mon Dec 11 00:00:00 UTC 2017
The Vascular Niche Regulates Hematopoietic Stem and Progenitor Cell Lodgment and Expansion via klf6a-ccl25b.
Developmental cell
Xue Y,Lv J,Zhang C,Wang L,Ma D,Liu F
25-5921-82 was used in Flow Cytometry to identify the Klf6a-Ccl25b/Ccr7 axis in controlling the complex HSPC-CHT niche interaction, which may be applicable to in vitro expansion or engraftment of HSPCs after transplantation.
Mon Aug 21 00:00:00 UTC 2017
Small molecule p300/catenin antagonist enhances hematopoietic recovery after radiation.
PloS one
Zhao Y,Wu K,Nguyen C,Smbatyan G,Melendez E,Higuchi Y,Chen Y,Kahn M
25-5921 was used in Flow cytometry/Cell sorting to report that the small molecule YH250 stimulates hematopoiesis in lethally or sublethally irradiated mice.
Tue Sep 26 00:00:00 UTC 2017
Age-dependent modulation of vascular niches for haematopoietic stem cells.
Nature
Kusumbe AP,Ramasamy SK,Itkin T,Mäe MA,Langen UH,Betsholtz C,Lapidot T,Adams RH
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Thu Apr 21 00:00:00 UTC 2016
Genetic lineage tracing identifies in situ Kit-expressing cardiomyocytes.
Cell research
Liu Q,Yang R,Huang X,Zhang H,He L,Zhang L,Tian X,Nie Y,Hu S,Yan Y,Zhang L,Qiao Z,Wang QD,Lui KO,Zhou B
25-5921 was used in Flow cytometry/Cell sorting to investigate the ability of CSCs to stimulate cardiac regeneration and repair.
Fri Jan 01 00:00:00 UTC 2016
Probing chromatin landscape reveals roles of endocardial TBX20 in septation.
The Journal of clinical investigation
Boogerd CJ,Aneas I,Sakabe N,Dirschinger RJ,Cheng QJ,Zhou B,Chen J,Nobrega MA,Evans SM
25-5921 was used in Flow cytometry/Cell sorting to investigate how TBX30 interacts with endocardial gene networks to drive the mesenchymal and myocardial movements essential for outflow tract and atrioventricular septation.
Mon Aug 01 00:00:00 UTC 2016
A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis.
Nature communications
Jeric I,Maurer G,Cavallo AL,Raguz J,Desideri E,Tarkowski B,Parrini M,Fischer I,Zatloukal K,Baccarini M
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Wed Dec 21 00:00:00 UTC 2016
Fat-associated lymphoid clusters control local IgM secretion during pleural infection and lung inflammation.
Nature communications
Jackson-Jones LH,Duncan SM,Magalhaes MS,Campbell SM,Maizels RM,McSorley HJ,Allen JE,Bénézech C
25-5921 was used in Flow cytometry/Cell sorting to reveal a link between inflammation, IL-33 release by FALC stromal cells, ILC2 activation and pleural B-cell activation in FALCs, resulting in local and antigen-specific IgM production.
Thu Sep 01 00:00:00 UTC 2016
PPAR-α and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal.
Nature
Lee HY,Gao X,Barrasa MI,Li H,Elmes RR,Peters LL,Lodish HF
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Thu Jun 25 00:00:00 UTC 2015
Cis-regulatory mechanisms governing stem and progenitor cell transitions.
Science advances
Johnson KD,Kong G,Gao X,Chang YI,Hewitt KJ,Sanalkumar R,Prathibha R,Ranheim EA,Dewey CN,Zhang J,Bresnick EH
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Tue Sep 01 00:00:00 UTC 2015
Genome-wide association study follow-up identifies cyclin A2 as a regulator of the transition through cytokinesis during terminal erythropoiesis.
American journal of hematology
Ludwig LS,Cho H,Wakabayashi A,Eng JC,Ulirsch JC,Fleming MD,Lodish HF,Sankaran VG
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Fri May 01 00:00:00 UTC 2015
Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis.
Cell death and differentiation
Cho J,Seo J,Lim CH,Yang L,Shiratsuchi T,Lee MH,Chowdhury RR,Kasahara H,Kim JS,Oh SP,Lee YJ,Terada N
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Tue Sep 01 00:00:00 UTC 2015
Excessive proliferation and impaired function of primitive hematopoietic cells in bone marrow due to senescence post chemotherapy in a T cell acute lymphoblastic leukemia model.
Journal of translational medicine
Jiang C,Hu X,Wang L,Cheng H,Lin Y,Pang Y,Yuan W,Cheng T,Wang J
25-5921 was used in Flow cytometry/Cell sorting to conclude that primitive hematopoietic cells in bone marrow enter proliferation earlier than leukemic cells after chemotherapy, and gradually lose their regenerative capacity partly by senescence due to accelerated cycling.
Fri Jul 17 00:00:00 UTC 2015
Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages.
Cell
Haldar M,Kohyama M,So AY,Kc W,Wu X,Briseño CG,Satpathy AT,Kretzer NM,Arase H,Rajasekaran NS,Wang L,Egawa T,Igarashi K,Baltimore D,Murphy TL,Murphy KM
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Thu Mar 13 00:00:00 UTC 2014
Developmental heterogeneity of cardiac fibroblasts does not predict pathological proliferation and activation.
Circulation research
Ali SR,Ranjbarvaziri S,Talkhabi M,Zhao P,Subat A,Hojjat A,Kamran P,Müller AM,Volz KS,Tang Z,Red-Horse K,Ardehali R
25-5921 was used in Flow cytometry/Cell sorting to study the developmental origins of cardiac fibroblasts and characterise their corresponding phenotypes, to aid in determining the proliferation rates of each developmental subset.
Fri Sep 12 00:00:00 UTC 2014
Purinergic P2Y₁₄ receptor modulates stress-induced hematopoietic stem/progenitor cell senescence.
The Journal of clinical investigation
Cho J,Yusuf R,Kook S,Attar E,Lee D,Park B,Cheng T,Scadden DT,Lee BC
25-5921 was used in Flow cytometry/Cell sorting to study the role of P2Y14 receptors on stem/progenitor cells in modifying cell senescence and cell death in response to tissue stress.
Tue Jul 01 00:00:00 UTC 2014
Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation.
Science translational medicine
Beale J,Jayaraman A,Jackson DJ,Macintyre JDR,Edwards MR,Walton RP,Zhu J,Man Ching Y,Shamji B,Edwards M,Westwick J,Cousins DJ,Yi Hwang Y,McKenzie A,Johnston SL,Bartlett NW
25-5921 was used in Flow cytometry/Cell sorting to demonstrate asthmatic epithelial cells have an increased intrinsic capacity for expression of a pro-type 2 cytokine in response to a viral infection.
Wed Oct 01 00:00:00 UTC 2014
Recruitment of bone marrow-derived cells to periodontal tissue defects.
Frontiers in cell and developmental biology
Kimura Y,Komaki M,Iwasaki K,Sata M,Izumi Y,Morita I
25-5921 was used in Flow cytometry/Cell sorting to reveal that BMCs are mobilised to periodontal tissue defects, and could be a new target of periodontal treatment.
Mon Nov 03 00:00:00 UTC 2014
Eosinophils regulate peripheral B cell numbers in both mice and humans.
Journal of immunology (Baltimore, Md. : 1950)
Wong TW,Doyle AD,Lee JJ,Jelinek DF
25-5921 was used in Flow cytometry/Cell sorting to assess the effect of eosinophils on B cell survival, proliferation, and Ig secretion.
Tue Apr 15 00:00:00 UTC 2014
Gene targeting study reveals unexpected expression of brain-expressed X-linked 2 in endocrine and tissue stem/progenitor cells in mice.
The Journal of biological chemistry
Ito K,Yamazaki S,Yamamoto R,Tajima Y,Yanagida A,Kobayashi T,Kato-Itoh M,Kakuta S,Iwakura Y,Nakauchi H,Kamiya A
25-5921 was used in Flow cytometry/Cell sorting to investigate the precise role and expression pattern of brain-expressed X-linked genes in endocrine and tissue stem/progenitor cells in mice.
Fri Oct 24 00:00:00 UTC 2014
Discriminating cellular heterogeneity using microwell-based RNA cytometry.
Nature communications
Dimov IK,Lu R,Lee EP,Seita J,Sahoo D,Park SM,Weissman IL,Lee LP
25-5921 was used in Flow cytometry/Cell sorting to develop a two-stage system to determine cellular heterogeneity.
Tue Mar 25 00:00:00 UTC 2014
Developmental stage determines efficiency of gene transfer to muscle satellite cells by in utero delivery of adeno-associated virus vector serotype 2/9.
Molecular therapy. Methods & clinical development
Stitelman DH,Brazelton T,Bora A,Traas J,Merianos D,Limberis M,Davey M,Flake AW
25-5921 was used in Flow cytometry/Cell sorting to study the efficiency of gene transfer via adeno-associated virus vector serotype 2/9 to muscle satellite cells at different developmental stages, to show that higher efficiency of transfer occurs at E16 when satellite cells (muscle stem cells) migrate.
Wed May 27 00:00:00 UTC 2015
Notch2 genetic fate mapping reveals two previously unrecognized mammary epithelial lineages.
Nature cell biology
Šale S,Lafkas D,Artavanis-Tsakonas S
25-5921 was used in Flow cytometry/Cell sorting to study the fate of cells expressing the Notch2 receptor paralogue, uncovering two novel mammary epithelial cell linages.
Wed May 01 00:00:00 UTC 2013
HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis.
Blood
Franke K,Kalucka J,Mamlouk S,Singh RP,Muschter A,Weidemann A,Iyengar V,Jahn S,Wieczorek K,Geiger K,Muders M,Sykes AM,Poitz DM,Ripich T,Otto T,Bergmann S,Breier G,Baretton G,Fong GH,Greaves DR,Bornstein S,Chavakis T,Fandrey J,Gassmann M,Wielockx B
25-5921 was used in Flow cytometry/Cell sorting to study the regulatory effects of oxygen-sensitive prolyl hydroxylases on the process of erythropoiesis.
Thu Feb 21 00:00:00 UTC 2013
Evidence for a multipotent mammary progenitor with pregnancy-specific activity.
Breast cancer research : BCR
Kaanta AS,Virtanen C,Selfors LM,Brugge JS,Neel BG
25-5921 was used in Flow cytometry/Cell sorting to provide data to show the existence of multi-potent mammary progenitor cells that have pregnancy-specific function.
Mon Dec 08 00:00:00 UTC 2014
Transgenic mammary epithelial osteopontin (spp1) expression induces proliferation and alveologenesis.
Genes & cancer
Hubbard NE,Chen QJ,Sickafoose LK,Wood MB,Gregg JP,Abrahamsson NM,Engelberg JA,Walls JE,Borowsky AD
25-5921 was used in Flow cytometry/Cell sorting to show that osteopontin mammary overexpressing mice provide a means to study the role of osteopontin in cancer progression.
Wed May 01 00:00:00 UTC 2013
CD8(+) T cell activation by murine erythroblasts infected with malaria parasites.
Scientific reports
Imai T,Ishida H,Suzue K,Hirai M,Taniguchi T,Okada H,Suzuki T,Shimokawa C,Hisaeda H
25-5921 was used in Flow cytometry/Cell sorting to examine the parasitism of erythroblasts by P. falciparum and P. vivax and the immune response towards them.
Mon Sep 16 00:00:00 UTC 2013
Concomitant inactivation of Rb and E2f8 in hematopoietic stem cells synergizes to induce severe anemia.
Blood
Hu T,Ghazaryan S,Sy C,Wiedmeyer C,Chang V,Wu L
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Thu May 10 00:00:00 UTC 2012
IKKα-mediated signaling circuitry regulates early B lymphopoiesis during hematopoiesis.
Blood
Balkhi MY,Willette-Brown J,Zhu F,Chen Z,Liu S,Guttridge DC,Karin M,Hu Y
25-5921-82 was used in Flow Cytometry to demonstrate that IKKα regulates B-lineage commitment via combined canonical and noncanonical NF-κB transcriptional activities to target Pax5 expression during hematopoiesis.
Thu Jun 07 00:00:00 UTC 2012
Nucleoside salvage pathway kinases regulate hematopoiesis by linking nucleotide metabolism with replication stress.
The Journal of experimental medicine
Austin WR,Armijo AL,Campbell DO,Singh AS,Hsieh T,Nathanson D,Herschman HR,Phelps ME,Witte ON,Czernin J,Radu CG
25-5921 was used in Flow cytometry/Cell sorting to investigate a functional link between nucleotide deficiency, replication stress, and two enzymes of the nucleoside salvage pathway: deoxycytidine kinase and thymidine kinase.
Mon Nov 19 00:00:00 UTC 2012
Origins and properties of dental, thymic, and bone marrow mesenchymal cells and their stem cells.
PloS one
Komada Y,Yamane T,Kadota D,Isono K,Takakura N,Hayashi S,Yamazaki H
25-5921 was used in Flow cytometry/Cell sorting to investigate whether mesechymal cells arise from neural crest or mesoderm, revealing the origins and properties of dental, thymic, and bone marrow mesenchymal cells.
Tue May 14 00:00:00 UTC 2013
Proteomic cornerstones of hematopoietic stem cell differentiation: distinct signatures of multipotent progenitors and myeloid committed cells.
Molecular & cellular proteomics : MCP
Klimmeck D,Hansson J,Raffel S,Vakhrushev SY,Trumpp A,Krijgsveld J
25-5921 was used in Flow cytometry/Cell sorting to discern the distinct signatures of multipotent progenitors and myeloid committed cells.
Wed Aug 01 00:00:00 UTC 2012
Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia.
Blood
Jaako P,Flygare J,Olsson K,Quere R,Ehinger M,Henson A,Ellis S,Schambach A,Baum C,Richter J,Larsson J,Bryder D,Karlsson S
25-5921 was used in Flow cytometry/Cell sorting to demonstrate the feasibility of transgenic RNA interference to generate models for diseases caused by haploinsufficient expression of a gene.
Thu Dec 01 00:00:00 UTC 2011
PML-RARA can increase hematopoietic self-renewal without causing a myeloproliferative disease in mice.
The Journal of clinical investigation
Welch JS,Yuan W,Ley TJ
25-5921 was used in Flow cytometry/Cell sorting to study a platform for more accurately dissecting the early events in acute promyelocytic leukemia pathogenesis.
Fri Apr 01 00:00:00 UTC 2011
Defective regulation of CXCR2 facilitates neutrophil release from bone marrow causing spontaneous inflammation in severely NF-kappa B-deficient mice.
Journal of immunology (Baltimore, Md. : 1950)
von Vietinghoff S,Asagiri M,Azar D,Hoffmann A,Ley K
25-5921 was used in Flow cytometry/Cell sorting to conclude that severe NF-kappaB deficiency facilitates neutrophil mobilization, ultimately leading to spontaneous inflammation.
Thu Jul 01 00:00:00 UTC 2010
Additive and global functions of HoxA cluster genes in mesoderm derivatives.
Developmental biology
Di-Poï N,Koch U,Radtke F,Duboule D
25-5921 was used in Flow cytometry/Cell sorting to report that mutant mice lacking the entire HoxA cluster in mesodermal lineages display the expected spectrum of postnatal respiratory, cardiac and urogenital defects, previously reported for single gene mutations.
Sat May 15 00:00:00 UTC 2010
Defective erythropoiesis in transgenic mice expressing dominant-negative upstream stimulatory factor.
Molecular and cellular biology
Liang SY,Moghimi B,Crusselle-Davis VJ,Lin IJ,Rosenberg MH,Li X,Strouboulis J,Huang S,Bungert J
25-5921 was used in Flow cytometry/Cell sorting to demonstrate that USF regulates globin gene expression indirectly by enhancing erythroid transcription factor expression and directly by mediating transcription complex recruitment.
Sun Nov 01 00:00:00 UTC 2009
Gfi1b alters histone methylation at target gene promoters and sites of gamma-satellite containing heterochromatin.
The EMBO journal
Vassen L,Fiolka K,Möröy T
Published figure using TER-119 monoclonal antibody (Product # 25-5921-82) in Flow Cytometry
Wed Jun 07 00:00:00 UTC 2006
