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            • Primary Antibodies ›
            • TRF1 Antibodies

            OriGene

            TERF1 Monoclonal Antibody (OTI3A1), TrueMAB™

            View all (17) TRF1 antibodies
            Datasheet
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            Catalog # TA812205
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            Price (USD)
            540.00
             
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            Cite TERF1 Monoclonal Antibody (OTI3A1), TrueMAB™

            • Antibody Testing Data (1)
            Application
            TERF1 Antibody in Western Blot (WB)
            Group 53 Created with Sketch.

            FIGURE: 1 / 1

            TERF1 Antibody (TA812205) in WB

            HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TERF1 (RC205904, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-TERF1. Positive lysates LY418833 (100 µg) and LC418833 (20 µg) can be purchased separately from OriGene.
            View Product

            TERF1 Antibody in Western Blot (WB)

            Product Details

            TA812205

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:2,000
            -
            Product Specifications

            Species Reactivity

            Human

            Host/Isotype

            Mouse / IgG2a

            Class

            Monoclonal

            Type

            Antibody

            Clone

            OTI3A1

            Immunogen

            Full length human recombinant protein of human TERF1 produced in HEK293T cell.
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            1 mg/mL

            Purification

            Affinity chromatography

            Storage buffer

            PBS with 1% BSA, 50% glycerol

            Contains

            0.02% sodium azide

            Storage conditions

            -20°C, Avoid Freeze/Thaw Cycles

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            Target Information

            This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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            Cite this product

            Bioinformatics

            Protein Aliases: FLJ41416; NIMA-interacting protein 2; Telomeric protein Pin2/TRF1; telomeric repeat binding factor (NIMA-interacting) 1; Telomeric repeat-binding factor 1; TTAGGG repeat-binding factor 1

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            Gene Aliases: hTRF1-AS; PIN2; t-TRF1; TERF1; TRBF1; TRF; TRF1

            View more View less

            UniProt ID: (Human) Q93029

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            Entrez Gene ID: (Human) 7013

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            Function(s)

            DNA binding double-stranded telomeric DNA binding telomerase activity protein binding DNA binding, bending telomeric DNA binding protein homodimerization activity ubiquitin binding G-rich strand telomeric DNA binding

            Process(es)

            telomere maintenance telomere maintenance via telomerase mitotic nuclear division negative regulation of DNA replication telomere capping telomeric loop formation negative regulation of telomere maintenance via telomerase negative regulation of telomere maintenance via semi-conservative replication response to drug meiotic telomere clustering cell division negative regulation of telomerase activity positive regulation of telosome assembly negative regulation of establishment of protein localization to telomere negative regulation of establishment of RNA localization to telomere negative regulation of establishment of macromolecular complex localization to telomere
            It has to be done as per old AB suggested Products section.
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            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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