Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: STQNNETELTS PILLPDLQIK ITNIFRPGFS PTADSLALKD SFCTHVTEAT KPEINKEDGE ILGFDIYSQP FGENADYPCE DKVDNIRQES GPVSNSEISL SFDLSR
Highest antigen sequence identity to the following orthologs - mouse 50%, rat 48%.
Required during spermatogenesis for normal chromosome synapsis and meiotic recombination in germ cells. Necessary for formation of DMC1 and RAD51 foci on meiotic chromosomes, suggesting a specific role in DNA double-stranded break repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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