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            • Primary Antibodies ›
            • TIGIT Antibodies

            NeoBiotechnologies

            TIGIT/VSTM3/VSIG9 (Immune Checkpoint for Cancer) Monoclonal Antibody (TIGIT/3017)

            View all (87) TIGIT antibodies
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            Cite TIGIT/VSTM3/VSIG9 (Immune Checkpoint for Cancer) Monoclonal Antibody (TIGIT/3017)

            • Antibody Testing Data (4)
            Application
            TIGIT/VSTM3/VSIG9 (Immune Checkpoint for Cancer) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Group 53 Created with Sketch.

            FIGURE: 1 / 4

            TIGIT/VSTM3/VSIG9 (Immune Checkpoint for Cancer) Antibody (201633-MSM1-P1ABX) in IHC (P)

            Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with TIGIT-Monospecific Mouse Monoclonal Antibody (TIGIT/3017).
            View Product

            TIGIT/VSTM3/VSIG9 (Immune Checkpoint for Cancer) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            TIGIT/VSTM3/VSIG9 (Immune Checkpoint for Cancer) Antibody in Flow Cytometry (Flow)
            TIGIT/VSTM3/VSIG9 (Immune Checkpoint for Cancer) Antibody in Peptide array (ARRAY)
            TIGIT/VSTM3/VSIG9 (Immune Checkpoint for Cancer) Antibody in SDS-PAGE (SDS-PAGE)

            Product Details

            201633-MSM1-P1ABX

            Applications
            Tested Dilution
            Publications

            Immunohistochemistry (Paraffin) (IHC (P))

            Assay-dependent
            -

            Immunohistochemistry (PFA fixed) (IHC (PFA))

            1-2 µg/mL
            -

            Flow Cytometry (Flow)

            1-2 µg/10^6 cells
            -

            ELISA (ELISA)

            Assay-dependent
            -

            Peptide Array (Array)

            Assay-dependent
            -
            Product Specifications

            Species Reactivity

            Human

            Host/Isotype

            Mouse / IgG2c, kappa

            Class

            Monoclonal

            Type

            Antibody

            Clone

            TIGIT/3017

            Immunogen

            Recombinant fragment (around aa 22-141) of human TIGIT protein.
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            1 mg/mL

            Purification

            Protein A/G

            Storage buffer

            PBS, pH 7.4

            Contains

            no preservative

            Storage conditions

            -20°C, Avoid Freeze/Thaw Cycles

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            Target Information

            Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: T cell immunoreceptor with Ig and ITIM domains; T-cell immunoreceptor with Ig and ITIM domains; V-set and immunoglobulin domain containing 9; V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain containing 3; V-set and transmembrane domain-containing protein 3; Washington University cell adhesion molecule

            View more View less

            Gene Aliases: TIGIT; VSIG9; VSTM3; WUCAM

            View more View less

            UniProt ID: (Human) Q495A1

            View more View less

            Entrez Gene ID: (Human) 201633

            View more View less

            Function(s)

            receptor activity receptor binding protein binding protein homodimerization activity cell adhesion molecule binding

            Process(es)

            homophilic cell adhesion via plasma membrane adhesion molecules heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules cell recognition negative regulation of interleukin-12 production positive regulation of interleukin-10 production negative regulation of T cell activation
            It has to be done as per old AB suggested Products section.
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