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Product Details
MA5-23931
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
211116
Immunogen
NS0 mouse myeloma cell line transfected with human TM4SF18 Met1-Ile201
Conjugate
Unconjugated
Form
Lyophilized
Concentration
0.5 mg/mL
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2606149
Product Specific Information
This antibody stains human TM4SF18-transfected cells but not parent cells.
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
Transmembrane 4 L Six Family Member 18 (TM4SF18) is a gene located on chromosome 11q12.3 that belongs to the transmembrane 4 L six superfamily, a group of proteins characterized by the presence of four transmembrane domains. TM4SF18 is expressed in various tissues and is involved in cellular processes such as cell adhesion, migration, and proliferation. As part of the tetraspanin family, TM4SF18 proteins play a role in organizing cellular membranes and facilitating interactions between cell surface receptors, impacting signaling pathways crucial for maintaining cellular functions and tissue homeostasis. Although TM4SF18's specific biological roles are still being elucidated, it has been implicated in tumorigenesis, where altered expression may influence cancer progression by modulating cell-cell communication and migration. Research into TM4SF18 aims to uncover its precise functions in health and disease, particularly its potential involvement in cancer biology and as a target for therapeutic interventions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AAB5; Transmembrane 4 L6 family member 18
Gene Aliases: L6D; TM4SF18
UniProt ID: (Human) Q96CE8
Entrez Gene ID: (Human) 116441
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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