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Immunogen sequence: TMNPHDIVQD AIHNFSPAYQ QYTQQSTLEP GPTWRGGAHG LSRSHSLSGA RDNEKTLLLS SDDEF
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.
TMEM184B, also known as C22orf5, is a 407 amino acid multi-pass membrane protein and represents a novel gene in the activation of the MAPK signaling pathway. The gene encoding TMEM184B maps to human chromosome 22; mutations in several of the genes in chromosome 22 are involved in the development of autism, schizophrenia, Phelan-McDermid syndrome and Neurofibromatosis type 2, suggesting that TMEM184B may play a role in these syndromes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CTA-447C4.2; Putative MAPK-activating protein FM08; Transmembrane protein 184B
Gene Aliases: C22orf5; FM08; HS5O6A; HSPC256; PSEC0108; TMEM184B
UniProt ID: (Human) Q9Y519
Entrez Gene ID: (Human) 25829
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