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TMEM189 Antibody (PA5-63746) in ICC/IF
Immunofluorescent staining of TMEM189 in human cell line U-2 OS using a TMEM189 Polyclonal Antibody (Product # PA5-63746) shows localization to endoplasmic reticulum.
产品信息
PA5-63746
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2648627
产品详细信息
Immunogen sequence: YFCITTGWLN YPLEKIGFWR RLEDLIQGLT GEKPRADDMK WAQKI
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 93%.
靶标信息
Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Multiple alternatively spliced transcripts encoding different isoforms have been described for this gene. A pseudogene has been identified which is also located on chromosome 20. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Plasmanylethanolamine desaturase 1; TMEM189; Transmembrane protein 189
基因别名: KUA; PDES; PEDS1; TMEM189
UniProt ID: (Human) A5PLL7
Entrez Gene ID: (Human) 387521
