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Invitrogen
TMEM189 Polyclonal Antibody
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Application
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TMEM189 Antibody (PA5-97031) in IHC (P)
Immunohistochemistry analysis of TMEM189 in paraffin-embedded human stomach. Samples were incubated with TMEM189 Polyclonal antibody (Product # PA5-97031) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-97031
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 171-270 of human TMEM189 (NP_9545801)
Conjugate
Unconjugated
Form
Liquid
Concentration
1.52 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2808833
Product Specific Information
Positive Samples: MCF7; Cellular Location: Endoplasmic reticulum membrane, Multi-pass membrane protein
Immunogen sequence: FVFCLIIFGT FTNQIHKWSH TYFGLPRWVT LLQDWHVILP RKHHRIHHVS PHETYFCITT GWLNYPLEKI GFWRRLEDLI QGLTGEKPRA DDMKWAQKIK
Target Information
Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Multiple alternatively spliced transcripts encoding different isoforms have been described for this gene. A pseudogene has been identified which is also located on chromosome 20. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Plasmanylethanolamine desaturase 1; TMEM189; Transmembrane protein 189
Gene Aliases: KUA; PDES; PEDS1; TMEM189
UniProt ID: (Human) A5PLL7
Entrez Gene ID: (Human) 387521
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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