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            • Primary Antibodies ›
            • TMEM259 Antibodies

            Invitrogen

            TMEM259 Polyclonal Antibody

            View all (5) TMEM259 antibodies
            Datasheet
            Protocols
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            Datasheet
            Protocols
            Questions & Answers

            Cite TMEM259 Polyclonal Antibody

            • Antibody Testing Data (2)
            Application
            TMEM259 Antibody in Immunohistochemistry (IHC)
            Group 53 Created with Sketch.

            FIGURE: 1 / 2

            TMEM259 Antibody (PA5-40831) in IHC

            Immunohistochemistry analysis of human kidney tissue using an anti-C19orf6 polyclonal antibody (Product # PA5-40831).
            View Product

            TMEM259 Antibody in Immunohistochemistry (IHC)
            TMEM259 Antibody in Western Blot (WB)

            Product Details

            PA5-40831

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1 µg/mL
            -

            Immunohistochemistry (IHC)

            5 µg/mL
            -
            Product Specifications

            Species Reactivity

            Human

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Synthetic peptide directed towards the middle region of human C19ORF6

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            1 mg/mL

            Purification

            Protein A

            Storage buffer

            PBS with 2% sucrose

            Contains

            0.09% sodium azide

            Storage conditions

            -20°C, Avoid Freeze/Thaw Cycles

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_2607557

            Product Specific Information

            Peptide sequence: YDDILMSSVK GLAENEENKG FLRNVVSGEH YRFVSMWMAR TSYLAAFAIM

            Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%

            Target Information

            Human membralin is unique and does not share significant sequence homology with other human genes, only membralins of other species. The membralin gene contains 11 exons which encode at least two spliced variants in human cancer. The long form of membralin (membralin-1) comprises all 11 exons, encoding a protein of 620-amino acids long and the short form of membralin (membralin-3) contains all exons except for exon 10, encoding a protein of 408 amino acids. Expression of different membralin isoforms depends on tissue type. The long form, membralin-1, is expressed in ovarian and colorectal carcinomas but not in breast or pancreatic carcinomas, which express only the short splice form, membralin-3. Recent studies suggest that membralin is a novel tumor-associated marker in ovarian serous carcinomas.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: aspecific BCL2 ARE-binding protein 1; Membralin; Transmembrane protein 259

            View more View less

            Gene Aliases: ASBABP1; C19orf6; MBRL; MEMBRALIN; R32184_3; TMEM259

            View more View less

            UniProt ID: (Human) Q4ZIN3

            View more View less

            Entrez Gene ID: (Human) 91304

            View more View less

            Function(s)

            non-motor microtubule binding protein

            Process(es)

            response to endoplasmic reticulum stress negative regulation of neuron death positive regulation of ERAD pathway
            It has to be done as per old AB suggested Products section.
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            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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