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            • Primary Antibodies ›
            • TMLHE Antibodies

            Invitrogen

            TMLHE Polyclonal Antibody

            View all (6) TMLHE antibodies
            Datasheet
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            Catalog # PA5-21461
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            Price (USD)
            483.00
            100 µL
             
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            Cite TMLHE Polyclonal Antibody

            • Antibody Testing Data (1)
            Application
            TMLHE Antibody in Western Blot (WB)
            Group 53 Created with Sketch.

            FIGURE: 1 / 1

            TMLHE Antibody (PA5-21461) in WB

            Western Blot using TMLHE Polyclonal Antibody (Product # PA5-21461). Sample (30 µg of whole cell lysate). A: HeLa S3. 12% SDS PAGE. TMLHE Polyclonal Antibody (Product # PA5-21461) diluted at 1:200.
            View Product

            TMLHE Antibody in Western Blot (WB)

            Product Details

            PA5-21461

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:100-1:1,000
            -
            Product Specifications

            Species Reactivity

            Human

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Recombinant protein encompassing a sequence within the center region of human TMLHE. The exact sequence is proprietary.

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            6.68 mg/mL

            Purification

            Protein A

            Storage buffer

            0.1M tris glycine, pH 7, with 10% glycerol

            Contains

            0.01% thimerosal

            Storage conditions

            Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_11154377

            Product Specific Information

            Recommended positive controls: H1299, HeLaS3, HepG2.

            Predicted reactivity: Mouse (95%), Rat (92%), Chicken (91%), Bovine (95%).

            Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

            Target Information

            This gene encodes the protein trimethyllysine dioxygenase which is the first enzyme in the carnitine biosynthesis pathway. Carnitine play an essential role in the transport of activated fatty acids across the inner mitochondrial membrane. The encoded protein converts trimethyllysine into hydroxytrimethyllysine. A pseudogene of this gene is found on chromosome X. Alternate splicing results in multiple transcript variants.

            ⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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            Cite this product

            Bioinformatics

            Protein Aliases: butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 2; Epsilon-trimethyllysine 2-oxoglutarate dioxygenase; Epsilon-trimethyllysine hydroxylase; TML dioxygenase; TML hydroxylase; TML-alpha-ketoglutarate dioxygenase; Trimethyllysine dioxygenase, mitochondrial

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            Gene Aliases: AUTSX6; BBOX2; TMLD; TMLH; TMLHE; TMLHED; XAP130

            View more View less

            UniProt ID: (Human) Q9NVH6

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            Entrez Gene ID: (Human) 55217

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            Function(s)

            iron ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen L-ascorbic acid binding trimethyllysine dioxygenase activity hydroxylase

            Process(es)

            carnitine biosynthetic process oxidation-reduction process
            It has to be done as per old AB suggested Products section.
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            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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