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Bioss
TMPRSS5 Polyclonal Antibody
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Product Details
BS-11183R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human TMPRSS5, amino acids 161-260.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Spinesin, also known as Serine protease 22 (PRSS22), is a gene located on chromosome 16p11.2 that encodes a trypsin-like serine protease predominantly expressed in the brain and airway tissues. This protease is part of the large family of serine proteases, characterized by their involvement in a variety of physiological processes, including digestion, immune response, and cellular remodeling. In the nervous system, Spinesin is implicated in synaptic function and plasticity, with potential roles in modulating neural connectivity and communication. It is also involved in processing extracellular matrix components, which can influence cell adhesion and migration, contributing to tissue remodeling and repair processes. Dysregulation of Spinesin expression or activity may impact neural development and has been associated with certain neurological disorders. Research into Spinesin continues to explore its specific functions in the nervous system and its potential therapeutic applications in neurobiology and regenerative medicine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adrenal mitochondrial protease; MGC141886; MGC148044; Spinesin; Transmembrane protease serine 5; transmembrane protease, serine 5 (spinesin)
Gene Aliases: Amp; SPINESIN; TMPRSS5
UniProt ID: (Human) Q9H3S3, (Mouse) Q9ER04
Entrez Gene ID: (Human) 80975, (Mouse) 80893, (Rat) 266681
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