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Immunogen sequence: ENVIREFNLN ELYQRAKKLS KAGDNIPEEQ PVASTPTTVS DGENKKDK
Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 79%.
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This protein is enriched on the mitochondria-associated-membrane of the ER via palmitoylation of two of its cytosolically exposed cysteines.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cell proliferation-inducing gene 26 protein; growth-inhibiting gene 11; protein disulfide isomerase family A, member 12; Thioredoxin domain-containing protein 14; Thioredoxin-related transmembrane protein 2
基因别名: CGI-31; My009; PDIA12; PIG26; PSEC0045; TMX2; TXNDC14; UNQ237/PRO270
UniProt ID: (Human) Q9Y320
Entrez Gene ID: (Human) 51075